A Phase 2a Proof-of-Concept Trial of Bempikibart (ADX-914) for the Treatment of Severe Alopecia Areata (SIGNAL-AA)
Public ClinicalTrials.gov record NCT06018428. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2a, Randomized, Double-blind, Placebo-Controlled, Proof-of-Concept Trial With Part B and Open-label Extension of Bempikibart (ADX-914) for the Treatment of Severe Alopecia Areata (SIGNAL-AA)
Study identification
- NCT ID
- NCT06018428
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Q32 Bio Inc.
- Industry
- Enrollment
- 75 participants
Conditions and interventions
Conditions
Interventions
- bempikibart (ADX-914) Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 11, 2023
- Primary completion
- May 31, 2026
- Completion
- Aug 31, 2026
- Last update posted
- May 7, 2026
2023 – 2026
United States locations
- U.S. sites
- 28
- U.S. states
- 16
- U.S. cities
- 27
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Scottsdale, Arizona | Scottsdale | Arizona | 85255 | — |
| Fayetteville, Arkansas | Fayetteville | Arkansas | 72703 | — |
| Hot Springs, Arkansas | Hot Springs | Arkansas | 71913 | — |
| Encinitas, California | Encinitas | California | 92024 | — |
| Fountain Valley, California | Fountain Valley | California | 92708 | — |
| Lomita, California | Lomita | California | 90717 | — |
| New Haven, Connecticut | New Haven | Connecticut | 06519 | — |
| Miami, Florida | Miami | Florida | 33173 | — |
| Tampa, Florida | Tampa | Florida | 33613 | — |
| Clarksville, Indiana | Clarksville | Indiana | 47129 | — |
| Bowling Green, Kentucky | Bowling Green | Kentucky | 42104 | — |
| Burlington, Massachusetts | Burlington | Massachusetts | 01805 | — |
| Troy, Michigan | Troy | Michigan | 48084 | — |
| Warren, Michigan | Warren | Michigan | 48192 | — |
| New York, New York | New York | New York | 10012 | — |
| New York, New York | New York | New York | 10023 | — |
| Wilmington, North Carolina | Wilmington | North Carolina | 28405 | — |
| Bexley, Ohio | Bexley | Ohio | 43209 | — |
| Clinical Trials | Canton | Ohio | 44718 | — |
| Mason, Ohio | Mason | Ohio | 45040 | — |
| Mayfield Heights, Ohio | Mayfield Heights | Ohio | 44124 | — |
| Portland, Oregon | Portland | Oregon | 97225 | — |
| Austin, Texas | Austin | Texas | 78759 | — |
| Frisco, Texas | Frisco | Texas | 75034 | — |
| Houston, Texas | Houston | Texas | 77056 | — |
| San Antonio, Texas | San Antonio | Texas | 78213 | — |
| Jordan, Utah | Jordan | Utah | 84095 | — |
| Spokane, Washington | Spokane | Washington | 99202 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 5 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06018428, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 7, 2026 · Synced May 9, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06018428 live on ClinicalTrials.gov.