An Efficacy, Safety, and Tolerability Study of Veligrotug (VRDN-001), in Participants With Chronic Thyroid Eye Disease (TED)
Public ClinicalTrials.gov record NCT06021054. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-masked, Placebo-controlled Safety, Tolerability, and Efficacy Study of VRDN-001, a Humanized Monoclonal Antibody Directed Against the IGF-1 Receptor, in Participants With Chronic Thyroid Eye Disease (TED)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a clinical trial assessing the efficacy, safety, and tolerability of an investigational drug, veligrotug (VRDN-001), in participants with chronic thyroid eye disease (TED).
Study identification
- NCT ID
- NCT06021054
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 188 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 1, 2023 (Actual)
- Primary completion
- Nov 4, 2024 (Actual)
- Completion
- Jul 25, 2025 (Actual)
- Last update posted
- Aug 13, 2026
2023 – 2025
United States locations
- U.S. sites
- 23
- U.S. states
- 12
- U.S. cities
- 19
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Advancing Research International, LLC | Los Angeles | California | 90023 | — |
| USC Roski Eye Institute | Los Angeles | California | 90089 | — |
| Amy Patel Jain, MD | Newport Beach | California | 92660 | — |
| Stanford Byers Eye Institute | Palo Alto | California | 94303 | — |
| Cockerham Eye Consultants, PC | San Diego | California | 92108 | — |
| Bascom Palmer Eye Institute - Ophthalmology - Miami | Miami | Florida | 33136 | — |
| Sarasota Retina Institute | Sarasota | Florida | 34239 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| Family Eye Physicians, Ltd | Oak Lawn | Illinois | 60453 | — |
| Massachusetts Eye and Ear | Boston | Massachusetts | 02114 | — |
| Ophthalmic Consultants of Boston | Boston | Massachusetts | 02189 | — |
| Michigan State University, Department of Neurology | East Lansing | Michigan | 48824 | — |
| Kahana Oculoplastic and Orbital Surgery | Livonia | Michigan | 48152 | — |
| Washington University School of Medicine in St Louis - Ophthalmology | St Louis | Missouri | 63110 | — |
| Steven Leibowitz, MD. | Las Vegas | Nevada | 89144 | — |
| Rutgers - New Jersey Medical School | Newark | New Jersey | 07103 | — |
| The Center for Eye and Facial Plastic Surgery | Somerset | New Jersey | 08873 | — |
| Department of Ophthalmology, University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Wills Eye Hospital | Philadelphia | Pennsylvania | 19107 | — |
| Baylor College of Medicine (BCM) - Ophthalmology | Houston | Texas | 77030 | — |
| Neuro Eye Clinical Trials | Houston | Texas | 77074 | — |
| University of Vermont Medical Center | Burlington | Vermont | 05401 | — |
| Harborview Medical Center | Seattle | Washington | 98104 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 34 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06021054, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 13, 2026 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06021054 live on ClinicalTrials.gov.