KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors
Public ClinicalTrials.gov record NCT06026410. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase 1, First-in-Human, Multicenter, Open-Label Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Antitumor Activity of KO-2806 When Administered as Monotherapy and in Combination Therapy in Adult Patients With Advanced Solid Tumors
Study identification
- NCT ID
- NCT06026410
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- Kura Oncology, Inc.
- Industry
- Enrollment
- 300 participants
Conditions and interventions
Conditions
Interventions
- Adagrasib Drug
- Cabozantinib Drug
- Darlifarnib Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 17, 2023
- Primary completion
- Dec 31, 2026
- Completion
- Mar 31, 2027
- Last update posted
- Apr 13, 2026
2023 – 2027
United States locations
- U.S. sites
- 23
- U.S. states
- 16
- U.S. cities
- 20
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Mayo Clinic Comprehensive Cancer Center | Phoenix | Arizona | 85054 | Recruiting |
| University of Arizona | Tucson | Arizona | 85721 | Recruiting |
| University of Arizona | Tucson | Arizona | 85724 | Recruiting |
| University of Southern California | Los Angeles | California | 90033 | Recruiting |
| Cedars-Sinai Medical Center | Los Angeles | California | 90048 | Recruiting |
| UCLA Department of Medicine | Los Angeles | California | 90095 | Recruiting |
| Sarah Cannon Research Institute at HealthONE | Denver | Colorado | 80218 | Recruiting |
| AdventHealth Celebration | Celebration | Florida | 34747 | Recruiting |
| Mayo Clinic Comprehensive Cancer Center | Jacksonville | Florida | 32224 | Recruiting |
| Florida Cancer Specialists | Sarasota | Florida | 34232 | Recruiting |
| University of Iowa Hospitals & Clinics | Iowa City | Iowa | 52242 | Recruiting |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02215 | Recruiting |
| Henry Ford Health System | Detroit | Michigan | 48202 | Recruiting |
| Mayo Clinic Comprehensive Cancer Center | Rochester | Minnesota | 55905 | Recruiting |
| Washington University School of Medicine | St Louis | Missouri | 63110 | Recruiting |
| Rutgers Cancer Institute of New Jersey | New Brunswick | New Jersey | 08901 | Recruiting |
| Ohio State University | Columbus | Ohio | 43210 | Recruiting |
| OU Stephenson Cancer Center | Oklahoma City | Oklahoma | 73104 | Recruiting |
| UPMC Hillman Cancer Center | Pittsburgh | Pennsylvania | 15232 | Recruiting |
| SCRI - Oncology Partners | Nashville | Tennessee | 37203 | Recruiting |
| UT Southwestern Simmons Cancer Center | Dallas | Texas | 75235 | Recruiting |
| MD Anderson Cancer Center | Houston | Texas | 77030 | Recruiting |
| University of Wisconsin (Carbone Cancer Center) | Madison | Wisconsin | 53792 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 17 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06026410, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 13, 2026 · Synced May 7, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06026410 live on ClinicalTrials.gov.