ClinicalTrials.gov record
Terminated Phase 2 Interventional Accepts healthy volunteers

Guanfacine for Hyperactivity in Children With Down Syndrome (HYPEbeGONE_DS)

ClinicalTrials.gov ID: NCT06042257

Public ClinicalTrials.gov record NCT06042257. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 20, 2026, 8:44 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Study identification

NCT ID
NCT06042257
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
Rachel G. Greenberg, MD, MB, MHS
Other
Enrollment
3 participants

Conditions and interventions

Interventions

  • Guanfacine Hydrochloride Immediate Release Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
6 Years to 12 Years
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 8, 2024
Primary completion
May 16, 2025
Completion
Aug 11, 2025
Last update posted
Apr 16, 2026

2024 – 2025

United States locations

U.S. sites
14
U.S. states
11
U.S. cities
14
Facility City State ZIP Site status
Phoenix Childrens Hospital Phoenix Arizona 85016
Emory University Atlanta Georgia 30322
Ann and Robert H. Lurie Hospital of Chicago Chicago Illinois 60611
University of Iowa Iowa City Iowa 52242
Kennedy Krieger Institute Baltimore Maryland 21205
Boston Children's Hospital Boston Massachusetts 02115
Massachusetts General Hospital Lexington Massachusetts 02421
Atrium Health-Wake Forest School of Medicine Charlotte North Carolina 28204
Duke University Hospital Durham North Carolina 27705
Akron Children's Hospital Akron Ohio 44308
Cincinnati Children's Hospital Cincinnati Ohio 45229
Virginia Center for Children Richmond Virginia 23220
University of Washington Seattle Washington 98195
University of Wisconsin Madison Madison Wisconsin 53792

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06042257, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 16, 2026 · Synced May 20, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06042257 live on ClinicalTrials.gov.

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