Massive Transfusion in Children-2: A Trial Examining Life Threatening Hemorrhage in Children
Public ClinicalTrials.gov record NCT06070350. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Massive Transfusion in Children: a Platform RCT of Whole Blood Compared to Component Therapy and Tranexamic Acid to Placebo in Life-threatening Traumatic Bleeding
Study identification
- NCT ID
- NCT06070350
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Philip Spinella
- Other
- Enrollment
- 1,000 participants
Conditions and interventions
Conditions
Interventions
- Component Therapy (CT) Biological
- Low Titer Group O Whole Blood (LTOWB) Biological
- Placebo Drug
- Tranexamic Acid (TXA) Drug
Biological · Drug
Eligibility (public fields only)
- Age range
- Up to 17 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 31, 2024
- Primary completion
- May 31, 2028
- Completion
- Sep 30, 2028
- Last update posted
- May 10, 2026
2024 – 2028
United States locations
- U.S. sites
- 23
- U.S. states
- 18
- U.S. cities
- 21
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Arizona | Tucson | Arizona | 84719 | Recruiting |
| Arkansas Children's Hospital | Little Rock | Arkansas | 72202 | Recruiting |
| University of California Davis | Sacramento | California | 95817 | Recruiting |
| Children's National Hospital | Washington D.C. | District of Columbia | 20010 | Recruiting |
| Emory University-Arthur M. Blank Hospital | Atlanta | Georgia | 30329 | Recruiting |
| Emory University-Scottish Rite Hospital | Atlanta | Georgia | 30342 | Recruiting |
| Tulane School of Medicine | New Orleans | Louisiana | 70118 | Recruiting |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216 | Recruiting |
| Washington University of St. Louis | St Louis | Missouri | 63110 | Recruiting |
| University of New Mexico | Albuquerque | New Mexico | 87131 | Recruiting |
| Wake Forest University Health Sciences | Wake Forest | North Carolina | 27157 | Recruiting |
| Nationwide Children's Hospital | Columbus | Ohio | 43205 | Recruiting |
| Oregon Health and Science University | Portland | Oregon | 97239 | Recruiting |
| Children's Hospital of Pittsburgh of UPMC | Pittsburgh | Pennsylvania | 15224 | Recruiting |
| LeBonheur Children's Hospital | Memphis | Tennessee | 38103 | Recruiting |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | Not yet recruiting |
| The University of Texas Southwestern Medical Center | Dallas | Texas | 75390 | Recruiting |
| Baylor College of Medicine | Houston | Texas | 77030 | Recruiting |
| Children's Memorial Hermann Hospital | Houston | Texas | 77030 | Recruiting |
| University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78229 | Recruiting |
| Primary Children's Hospital | Salt Lake City | Utah | 84112 | Recruiting |
| University of Washington Harborview | Seattle | Washington | 98195 | Recruiting |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06070350, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 10, 2026 · Synced May 21, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06070350 live on ClinicalTrials.gov.