A Study to Evaluate Avacopan in Participants With ANCA-associated Vasculitis

ClinicalTrials.gov ID: NCT06072482

Public ClinicalTrials.gov record NCT06072482. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

View official ClinicalTrials.gov record → Back to search

ClinicalTrials.gov public records Last synced Apr 29, 2026, 12:46 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-blind, Placebo-controlled Phase 4 Clinical Trial to Evaluate the Long-term Safety and Efficacy of Avacopan in Participants With Antineutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis

Study identification

NCT ID: NCT06072482
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 4
Lead sponsor: Amgen; Industry
Enrollment: 300 participants

Conditions and interventions

Conditions

Antineutrophil Cytoplasmic Antibody-associated Vasculitis

Interventions

Avacopan Drug
Placebo Drug
Standard of Care Drug

Drug

Eligibility (public fields only)

Age range: 18 Years to 100 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Feb 6, 2024
Primary completion: Dec 30, 2036
Completion: Dec 30, 2036
Last update posted: Apr 27, 2026

2024 – 2036

United States locations

U.S. sites: 58
U.S. states: 31
U.S. cities: 56

Facility	City	State	ZIP	Site status
Orthopedic Physicians Alaska	Anchorage	Alaska	99508	Terminated
Scottsdale Healthcare at Shea - HonorHealth	Scottsdale	Arizona	85258	Recruiting
Southwest Kidney Institute	Surprise	Arizona	85374	Recruiting
Unity Health	Searcy	Arkansas	72143	Recruiting
Medvin Clinical Research	Covina	California	91722	Recruiting
Palo Alto Medical Foundation Fremont	Fremont	California	94538	Recruiting
The Nephrology Group	Fresno	California	93720	Recruiting
Providence Medical Foundation	Fullerton	California	92835	Recruiting
Medvin Clinical Research	Menifee	California	92586	Recruiting
University of California San Francisco- Zuckerburg San Francisco General	San Francisco	California	94110	Recruiting
Harbor University of California at Los Angeles Medical Center	Torrance	California	90502	Recruiting
University of Colorado	Aurora	Colorado	80045	Recruiting
Florida Kidney Physicians	Boca Raton	Florida	33431	Recruiting
Malcom Randall Veterans Affairs Medical Center	Gainesville	Florida	32608	Recruiting
Mayo Clinic	Jacksonville	Florida	32224	Recruiting
ClinTrial Research Oakwater, Llc	Orlando	Florida	32806	Recruiting
University of South Florida	Tampa	Florida	33606	Recruiting
Emory University	Atlanta	Georgia	30322	Recruiting
Lake Cumberland Rheumatology	New Albany	Indiana	47150	Recruiting
University of Iowa Hospitals and Clinics	Iowa City	Iowa	52242	Recruiting
Dunes Clinical Research LLC	Sioux City	Iowa	51104	Recruiting
University of Kentucky	Lexington	Kentucky	40536	Recruiting
Johns Hopkins Bayview Medical Center	Baltimore	Maryland	21224	Recruiting
Massachusetts General Hospital	Boston	Massachusetts	02114	Recruiting
Brigham and Womens Hospital	Boston	Massachusetts	02115	Recruiting
Henry Ford Health System	Detroit	Michigan	48202	Recruiting
Kidney Michigan Institute	Saginaw	Michigan	49804	Recruiting
Clinical Research Institute of Michigan	Saint Clair Shores	Michigan	48081	Recruiting
Revive Research Institute	Sterling Heights	Michigan	48313	Recruiting
University of Minnesota	Minneapolis	Minnesota	55414	Recruiting
Mayo Clinic	Rochester	Minnesota	55905	Recruiting
Renown Rheumatology	Reno	Nevada	89502	Recruiting
Dartmouth Hitchcock Medical Center	Lebanon	New Hampshire	03766	Recruiting
Renal Medicine Associates	Albuquerque	New Mexico	87109	Recruiting
New York Nephrology Vasculitis and Glomerular Center	Albany	New York	12209	Recruiting
Northwell Health	Great Neck	New York	11021	Recruiting
Hospital For Special Surgery	New York	New York	10021	Recruiting
East Carolina University Brody Outpatient Center	Greenville	North Carolina	27834	Recruiting
Brookview Hills Research Associates Llc	Winston-Salem	North Carolina	27103	Recruiting
University Hospitals Cleveland Medical Center	Cleveland	Ohio	44106	Recruiting
The Ohio State University	Columbus	Ohio	43201	Recruiting
Stat Research	Miamisburg	Ohio	45342	Recruiting
Hightower Clinical	Oklahoma City	Oklahoma	73114	Recruiting
Oregon Health and Science University	Portland	Oregon	97239	Recruiting
University of Pennsylvania	Philadelphia	Pennsylvania	19104	Recruiting
Allegheny Health Network Cancer Institute at Mellon Pavilion	Pittsburgh	Pennsylvania	15224	Recruiting
University of Pittsburgh Medical Center	Pittsburgh	Pennsylvania	15232	Recruiting
Nephrology Associates Inc	East Providence	Rhode Island	02914	Recruiting
Medical University of South Carolina	Charleston	South Carolina	29425	Recruiting
West Tennessee Research Institute	Jackson	Tennessee	38305	Recruiting
Vanderbilt University Medical Center	Nashville	Tennessee	37232	Recruiting
Vital Rheumatology	Austin	Texas	78727	Recruiting
Renal Disease Research Institute - Landry Office	Dallas	Texas	75204	Recruiting
Scott and White Memorial Hospital	Temple	Texas	76502	Recruiting
Nephrology Associates of Northern Virginia Inc	Fairfax	Virginia	22033	Recruiting
Virginia Mason Medical Center	Seattle	Washington	98101	Terminated
Rheumatology and Pulmonary Clinic	Beckley	West Virginia	25801	Recruiting
Medical College of Wisconsin	Milwaukee	Wisconsin	53226	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 18 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT06072482, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Apr 27, 2026 · Synced Apr 29, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06072482 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →