Study of Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Obinutuzumab in Participants With Chronic Lymphocytic Leukemia (CLL)
Public ClinicalTrials.gov record NCT06073821. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Open-Label, Randomized Study of Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Obinutuzumab in Patients With Previously Untreated Chronic Lymphocytic Leukemia
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The main objective of this study is to compare the efficacy of sonrotoclax plus zanubrutinib versus venetoclax plus obinutuzumab in participants with chronic lymphocytic leukemia (CLL)
Study identification
- NCT ID
- NCT06073821
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 652 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 11, 2023 (Actual)
- Primary completion
- Feb 2032 (Estimated)
- Completion
- Dec 2032 (Estimated)
- Last update posted
- Oct 14, 2026
2023 – 2032
United States locations
- U.S. sites
- 40
- U.S. states
- 25
- U.S. cities
- 38
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Alaska Oncology and Hematology, Llc | Anchorage | Alaska | 99508-2974 | — |
| City of Hope National Medical Center | Duarte | California | 91010-3012 | — |
| University of California San Diego (Ucsd) Moores Cancer Center | La Jolla | California | 92093-1503 | — |
| Valkyrie Clinical Trials | Los Angeles | California | 90067-2011 | — |
| UCLA Department of Medicine Hematologyoncology | Los Angeles | California | 90095-3075 | — |
| Chao Family Comprehensive Cancer Center | Orange | California | 92868-3201 | — |
| Stanford Medicine | Palo Alto | California | 94304-2205 | — |
| University of Colorado Cancer Center | Aurora | Colorado | 80045-2517 | — |
| Medstar Georgetown University Hospital | Washington D.C. | District of Columbia | 20007-2113 | — |
| Mount Sinai Medical Center Braman Comprehensive Cancer Center | Miami | Florida | 33140 | — |
| Moffitt Cancer Center | Tampa | Florida | 33612-9496 | — |
| Southeastern Regional Medical Center | Newnan | Georgia | 30265-8001 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| Illinois Cancercare, Pc | Peoria | Illinois | 61615-7822 | — |
| Fort Wayne Medical Oncology and Hematology | Fort Wayne | Indiana | 46804 | — |
| University of Iowa Hospitals and Clinics | Iowa City | Iowa | 52242-1009 | — |
| Mission Cancer and Blood | Waukee | Iowa | 50263 | — |
| The University of Kansas Cancer Center | Westwood | Kansas | 66205-2003 | — |
| Norton Cancer Institute Pavilion | Louisville | Kentucky | 40207-4700 | — |
| Ochsner Clinic Foundation | New Orleans | Louisiana | 70121-2429 | — |
| University of Minnesota | Minneapolis | Minnesota | 55455-0341 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110-1010 | — |
| John Theurer Cancer Center Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| Rutgers Cancer Institute of New Jersey | New Brunswick | New Jersey | 08901-1914 | — |
| Columbia University Medical Center | New York | New York | 10032 | — |
| Optum Medical Care, Pc | Westbury | New York | 11590-5119 | — |
| University of North Carolina At Chapel Hill | Chapel Hill | North Carolina | 27514-4220 | — |
| Atrium Health Levine Cancer Institute (Lci) | Charlotte | North Carolina | 28204-2990 | — |
| Duke University Medical Center | Durham | North Carolina | 27705-3976 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195-0001 | — |
| The James Cancer Hospital and Solove Research Institute At Ohio State University | Columbus | Ohio | 43210-1240 | — |
| Oncology Associates of Oregon Willamette Valley Cancer Center | Eugene | Oregon | 97401 | — |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111-2434 | — |
| Scri Tennessee Oncology Chattanooga | Chattanooga | Tennessee | 37404-1130 | — |
| Huntsman Cancer Institute | Salt Lake City | Utah | 84112-5550 | — |
| Virginia Cancer Institute | Richmond | Virginia | 23229-8605 | — |
| Vcu Health System Massey Comprehensive Cancer Center | Richmond | Virginia | 23298-5004 | — |
| Fred Hutchinson Cancer Research Center | Seattle | Washington | 98109-4433 | — |
| Gunderson Health System | La Crosse | Wisconsin | 54601-5467 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226-3522 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 161 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06073821, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 14, 2026 · Synced Oct 27, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06073821 live on ClinicalTrials.gov.