Study on Efficacy and Safety of Givinostat Versus Hydroxyurea in Patients With Polycythemia Vera
Public ClinicalTrials.gov record NCT06093672. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Randomized, Open-label, Multicenter Phase 3 Study to Assess the Efficacy and Safety of GIVinostat Versus Hydroxyurea IN JAK2V617F-positive High-risk Polycythemia Vera Patients: the GIV-IN PV TRIAL
Study identification
- NCT ID
- NCT06093672
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Italfarmaco
- Industry
- Enrollment
- 220 participants
Conditions and interventions
Conditions
Interventions
- Givinostat Drug
- Hydroxyurea Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 25, 2024
- Primary completion
- Jun 30, 2026
- Completion
- Jun 30, 2026
- Last update posted
- Mar 24, 2026
2024 – 2026
United States locations
- U.S. sites
- 14
- U.S. states
- 12
- U.S. cities
- 13
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35294-0001 | Not yet recruiting |
| Emad Ibrahim, MD, Inc | Redlands | California | 92373 | Recruiting |
| US Oncology Inc | Englewood | Colorado | 80113 | Recruiting |
| American Oncology Partners of Maryland, PA | Bethesda | Maryland | 20852 | Recruiting |
| Icahn School of Medicine at Mount Sinai | New York | New York | 10029 | Recruiting |
| University of North Carolina at Chapel Hill | Chapel Hill | North Carolina | 27599 | Recruiting |
| The Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | Recruiting |
| Oncology Associates of Oregon, P.C. | Eugene | Oregon | 97401 | Recruiting |
| MD Anderson Cancer Center | Houston | Texas | 77030 | Recruiting |
| Texas Oncology (Webster) - USOR | Houston | Texas | 77089 | Recruiting |
| Texas Oncology-Denison Cancer Center | Sherman | Texas | 75090 | Recruiting |
| University of Utah - Huntsman Cancer Institute - PPDS | Salt Lake City | Utah | 84112 | Recruiting |
| The James Cancer Hospital and Solove Research Institute | Roanoke | Virginia | 43210 | Recruiting |
| VA Puget Sound Health Care System - NAVREF - PPDS | Seattle | Washington | 98108-1532 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 76 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06093672, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 24, 2026 · Synced May 17, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06093672 live on ClinicalTrials.gov.