Study to Assess Adverse Events and Change in Disease Activity in Previously Treated Adult Participants Receiving Intravenous (IV) ABBV-400 With Unresectable Metastatic Colorectal Cancer in Combination With IV Fluorouracil, Folinic Acid, and Bevacizumab
Public ClinicalTrials.gov record NCT06107413. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Randomized Study to Evaluate Safety, Efficacy, and Optimal Dose of ABBV-400 in Combination With Fluorouracil, Folinic Acid, and Bevacizumab and to Evaluate Safety and Efficacy of ABBV-400 in Combination With Bevacizumab in Previously Treated Subjects With Unresectable Metastatic Colorectal Cancer
Study identification
- NCT ID
- NCT06107413
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- AbbVie
- Industry
- Enrollment
- 280 participants
Conditions and interventions
Conditions
Interventions
- ABBV-400 Drug
- Bevacizumab Drug
- Fluorouracil Drug
- Folinic Acid Drug
- Irinotecan Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 11, 2023
- Primary completion
- Nov 30, 2026
- Completion
- Nov 30, 2026
- Last update posted
- Dec 11, 2025
2023 – 2026
United States locations
- U.S. sites
- 22
- U.S. states
- 15
- U.S. cities
- 18
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Mayo Clinic Arizona /ID# 262610 | Phoenix | Arizona | 85054 | — |
| Highlands Oncology Group, PA /ID# 259424 | Springdale | Arkansas | 72762 | — |
| City of Hope National Medical Center /ID# 257576 | Duarte | California | 91010 | — |
| City of Hope - Orange County Lennar Foundation Cancer Center /ID# 268365 | Irvine | California | 92618 | — |
| Yale School of Medicine /ID# 257494 | New Haven | Connecticut | 06519 | — |
| Mayo Clinic Hospital Jacksonville /ID# 262609 | Jacksonville | Florida | 32224 | — |
| University of Illinois Hospital and Health Sciences System /ID# 257300 | Chicago | Illinois | 60607 | — |
| Northwestern Medicine - Northwestern Memorial Hospital /ID# 260563 | Chicago | Illinois | 60611 | — |
| Fort Wayne Medical Oncology and Hematology- South Office /ID# 259601 | Fort Wayne | Indiana | 46804 | — |
| Indiana University Melvin and Bren Simon Cancer Center /ID# 258789 | Indianapolis | Indiana | 46202-5116 | — |
| Community Health Network, Inc. /ID# 257078 | Indianapolis | Indiana | 46250-2042 | — |
| Comprehensive Cancer Centers of Nevada /ID# 257642 | Henderson | Louisiana | 89052 | — |
| Mayo Clinic - Rochester /ID# 257301 | Rochester | Minnesota | 55905-0001 | — |
| Atrium Health Levine Cancer Institute /ID# 258840 | Charlotte | North Carolina | 28204 | — |
| Duke Cancer Institute /ID# 257236 | Durham | North Carolina | 27710 | — |
| Oregon Health & Science University, Knight Cancer Institute- /ID# 259190 | Portland | Oregon | 97239 | — |
| Medical University of South Carolina /ID# 258486 | Charleston | South Carolina | 29425 | — |
| Avera Cancer Institute /ID# 257949 | Sioux Falls | South Dakota | 57105 | — |
| MD Anderson Cancer Center /ID# 258713 | Houston | Texas | 77030 | — |
| Texas Oncology PA /ID# 257780 | Houston | Texas | 77090-3063 | — |
| Inova Schar Cancer Institute - Fairfax - Innovation Park Drive /ID# 257448 | Fairfax | Virginia | 22031 | — |
| Virginia Cancer Specialists - Fairfax /ID# 257261 | Fairfax | Virginia | 22031 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 42 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06107413, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 11, 2025 · Synced May 6, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06107413 live on ClinicalTrials.gov.