Study to Evaluate Safety, Tolerability and Drug Levels of BMS-986435/MYK-224 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)
Public ClinicalTrials.gov record NCT06122779. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2A, Double-blind, Randomized, Placebo-controlled, Multi-center Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BMS-986435/MYK-224 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the safety, tolerability, and exposure-response (E-R) of BMS-986435/MYK-224 in participants with symptomatic Heart Failure with Preserved Ejection Fraction (HFpEF).
Study identification
- NCT ID
- NCT06122779
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 227 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 40 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 6, 2023
- Primary completion
- Dec 13, 2026
- Completion
- Dec 13, 2026
- Last update posted
- Jul 29, 2026
2023 – 2026
United States locations
- U.S. sites
- 23
- U.S. states
- 13
- U.S. cities
- 21
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Local Institution - 0002 | Birmingham | Alabama | 35233 | — |
| Local Institution - 0096 | Lakewood | Colorado | 80228-1710 | — |
| Local Institution - 0077 | Jacksonville | Florida | 32204-4748 | — |
| Local Institution - 0003 | Miami | Florida | 33133-4223 | — |
| Local Institution - 0099 | Miami | Florida | 33136-2107 | — |
| Local Institution - 0004 | Chicago | Illinois | 60611-5969 | — |
| Local Institution - 0005 | Hazel Crest | Illinois | 60429-2196 | — |
| Local Institution - 0029 | Indianapolis | Indiana | 46260-1992 | — |
| Local Institution - 0028 | St Louis | Missouri | 63136-6111 | — |
| Local Institution - 0117 | Hackensack | New Jersey | 07601-1915 | — |
| Local Institution - 0070 | Albany | New York | 12211 | — |
| Local Institution - 0105 | Brooklyn | New York | 11215 | — |
| Local Institution - 0008 | New York | New York | 10065-4805 | — |
| Local Institution - 0059 | Rochester | New York | 14618-2668 | — |
| Local Institution - 0076 | Rochester | New York | 14621 | — |
| Local Institution - 0094 | Rosedale | New York | 11422-1320 | — |
| Local Institution - 0095 | Durham | North Carolina | 27710-4000 | — |
| Local Institution - 0016 | Oklahoma City | Oklahoma | 73135-2607 | — |
| Local Institution - 0078 | Abington | Pennsylvania | 19001 | — |
| Local Institution - 0001 | Tullahoma | Tennessee | 37388-8260 | — |
| Local Institution - 0104 | Austin | Texas | 78756-4080 | — |
| Local Institution - 0036 | Dallas | Texas | 75390 | — |
| Local Institution - 0015 | Houston | Texas | 77025-5253 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 63 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06122779, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 29, 2026 · Synced Sep 10, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06122779 live on ClinicalTrials.gov.