Study to Evaluate Safety, Tolerability and Drug Levels of BMS-986435/MYK-224 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)
Public ClinicalTrials.gov record NCT06122779. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2A, Double-blind, Randomized, Placebo-controlled, Multi-center Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BMS-986435/MYK-224 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)
Study identification
- NCT ID
- NCT06122779
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Bristol-Myers Squibb
- Industry
- Enrollment
- 208 participants
Conditions and interventions
Conditions
Interventions
- BMS-986435 Drug
- Placebo Other
Drug · Other
Eligibility (public fields only)
- Age range
- 40 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 6, 2023
- Primary completion
- Jul 2, 2026
- Completion
- Jul 2, 2026
- Last update posted
- May 7, 2026
2023 – 2026
United States locations
- U.S. sites
- 31
- U.S. states
- 16
- U.S. cities
- 24
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35233 | Recruiting |
| Colorado Heart and Vascular - Lakewood | Lakewood | Colorado | 80228-1710 | Recruiting |
| Ascension St. Vincent's Riverside Hospital - PPDS | Jacksonville | Florida | 32204-4748 | Recruiting |
| Local Institution - 0003 | Miami | Florida | 33133-4223 | Active, not recruiting |
| University of Miami FL Miller School of Medicine -1120 NW 14th St | Miami | Florida | 33136-2107 | Recruiting |
| Local Institution - 0014 | Atlanta | Georgia | 30322-1013 | Withdrawn |
| Local Institution - 0048 | Atlanta | Georgia | 30322-1013 | Withdrawn |
| Bluhm Cardiovascular Institute of Northwestern | Chicago | Illinois | 60611-5969 | Recruiting |
| Chicago Medical Research, LLC - Hazel Crest | Hazel Crest | Illinois | 60429-2196 | Recruiting |
| Ascension Medical Group St. Vincent - Indianapolis Heart Care | Indianapolis | Indiana | 46260-1992 | Recruiting |
| Local Institution - 0045 | Indianapolis | Indiana | 46260-1992 | Withdrawn |
| St. Louis Heart and Vascular | St Louis | Missouri | 63136-6111 | Recruiting |
| Local Institution - 0043 | St Louis | Missouri | 63136 | Withdrawn |
| Local Institution - 0117 | Hackensack | New Jersey | 07601-1915 | Not yet recruiting |
| Capital Cardiology Associates | Albany | New York | 12211 | Recruiting |
| Local Institution - 0105 | Brooklyn | New York | 11215 | Not yet recruiting |
| Weill Cornell Medicine | New York | New York | 10065-4805 | Recruiting |
| University of Rochester Medical Center - PPDS | Rochester | New York | 14618-2668 | Recruiting |
| Rochester General Hospital Center for Clinical Research | Rochester | New York | 14621 | Recruiting |
| Laurelton Heart Specialist PC - MyClinical - PPDS | Rosedale | New York | 11422-1320 | Recruiting |
| Duke Cardiology Clinic - PPDS | Durham | North Carolina | 27710-4000 | Recruiting |
| Local Institution - 0058 | Cincinnati | Ohio | 45242 | Withdrawn |
| Local Institution - 0041 | Oklahoma City | Oklahoma | 73135-2607 | Withdrawn |
| South Oklahoma Heart Research | Oklahoma City | Oklahoma | 73135-2607 | Recruiting |
| Abington Memorial Hospital | Abington | Pennsylvania | 19001 | Recruiting |
| Tennessee Center for Clinical Trials | Tullahoma | Tennessee | 37388-8260 | Recruiting |
| Local Institution - 0104 | Austin | Texas | 78756-4080 | Not yet recruiting |
| University of Texas Southwestern Medical Center | Dallas | Texas | 75390 | Recruiting |
| Angiocardiac Care of Texas - PA - PPDS | Houston | Texas | 77025-5253 | Recruiting |
| Local Institution - 0051 | Houston | Texas | 77025-5253 | Withdrawn |
| Local Institution - 0066 | Falls Church | Virginia | 22042-1262 | Withdrawn |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 86 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06122779, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 7, 2026 · Synced May 10, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06122779 live on ClinicalTrials.gov.