A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors
Public ClinicalTrials.gov record NCT06131840. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Open-label Phase 1 Study to Investigate PF-08046050 (SGN-CEACAM5C) in Adults With Advanced Solid Tumors
Study identification
- NCT ID
- NCT06131840
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- Seagen, a wholly owned subsidiary of Pfizer
- Industry
- Enrollment
- 914 participants
Conditions and interventions
Conditions
Interventions
- 5-Fluorouracil (5-FU) Drug
- Leucovorin (LV) Drug
- Oxaliplatin Drug
- PF-08046050 Drug
- bevacizumab Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 19, 2023
- Primary completion
- Sep 11, 2029
- Completion
- Sep 11, 2030
- Last update posted
- Apr 19, 2026
2023 – 2030
United States locations
- U.S. sites
- 21
- U.S. states
- 11
- U.S. cities
- 14
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Mayo Clinic Hospital | Phoenix | Arizona | 85054 | Recruiting |
| Mayo Clinic | Scottsdale | Arizona | 85259 | Recruiting |
| City of Hope (City of Hope National Medical Center, City of Hope Medical Center) | Duarte | California | 91010 | Recruiting |
| IP Address: City of Hope Investigational Drug Services(IDS) | Duarte | California | 91010 | Recruiting |
| University of Colorado Hospital - Anschutz Cancer Pavilion (ACP) | Aurora | Colorado | 80045 | Recruiting |
| University of Colorado Hospital | Aurora | Colorado | 80045 | Recruiting |
| Florida Cancer Specialists | Orlando | Florida | 32827 | Recruiting |
| Sarah Cannon Research Institute at Florida Cancer Specialists | Orlando | Florida | 32827 | Recruiting |
| Sidney Kimmel Comprehensive Cancer at Johns Hopkins | Baltimore | Maryland | 21287 | Recruiting |
| The Johns Hopkins University | Baltimore | Maryland | 21287 | Recruiting |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02115 | Recruiting |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | Recruiting |
| START Midwest | Grand Rapids | Michigan | 49546 | Recruiting |
| Mayo Clinic Cancer Center | Rochester | Minnesota | 55905 | Recruiting |
| Mayo Clinic | Rochester | Minnesota | 55905 | Recruiting |
| Sarah Cannon Research Institute - Pharmacy | Nashville | Tennessee | 37203 | Recruiting |
| SCRI Oncology Partners | Nashville | Tennessee | 37203 | Recruiting |
| The University of Texas MD Anderson Cancer Center | Houston | Texas | 77030 | Recruiting |
| South Texas Accelerated Research Therapeutics, LLC | San Antonio | Texas | 78229 | Recruiting |
| START Mountain Region | Salt Lake City | Utah | 84119 | Recruiting |
| South Texas Accelerated Research Therapeutics Mountain Region | West Valley City | Utah | 84119 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 23 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06131840, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 19, 2026 · Synced Apr 30, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06131840 live on ClinicalTrials.gov.