A Study to Learn About the Study Medicine Called PF-07868489 in Healthy Adult People and in People With Pulmonary Arterial Hypertension
Public ClinicalTrials.gov record NCT06137742. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A PHASE 1 / 2, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF SINGLE ESCALATING DOSES OF PF-07868489 IN HEALTHY ADULT PARTICIPANTS AND, ADDITIONALLY, CLINICAL ACTIVITY OF REPEAT DOSES IN PARTICIPANTS WITH PULMONARY ARTERIAL HYPERTENSION
Study identification
- NCT ID
- NCT06137742
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Lead sponsor
- Pfizer
- Industry
- Enrollment
- 97 participants
Conditions and interventions
Conditions
Interventions
- PF-07868489 Drug
- Placebo for PF-07868489 Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 16, 2023
- Primary completion
- Sep 1, 2026
- Completion
- Sep 1, 2026
- Last update posted
- May 4, 2026
2023 – 2026
United States locations
- U.S. sites
- 13
- U.S. states
- 7
- U.S. cities
- 10
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Anaheim Clinical Trials, LLC | Anaheim | California | 92801 | — |
| UCI Health Center for Innovative Health Therapies (CIHT) | Orange | California | 92868 | — |
| UC Davis Health Medical Center | Sacramento | California | 95817 | — |
| UCSF Health St. Mary's Hospital | San Francisco | California | 94117 | — |
| University of Colorado Anschutz Medical Campus | Aurora | Colorado | 80045 | — |
| Norton Hospital | Louisville | Kentucky | 40202 | — |
| Mount Sinai Hospital | New York | New York | 10029 | — |
| Eastowne Medical Office Building - Clinical Research Unit | Chapel Hill | North Carolina | 27514 | — |
| UNC Hospitals | Chapel Hill | North Carolina | 27514 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02903 | — |
| Center for Advanced Lung Care | Providence | Rhode Island | 02904 | — |
| Medical University of South Carolina - Radiology | Charleston | South Carolina | 29425 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 18 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06137742, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 4, 2026 · Synced May 8, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06137742 live on ClinicalTrials.gov.