A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight
Public ClinicalTrials.gov record NCT06143956. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Master Protocol for a Randomized, Controlled, Clinical Trial of Multiple Interventions for Chronic Weight Management in Adult Participants With Obesity or Overweight
Study identification
- NCT ID
- NCT06143956
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Eli Lilly and Company
- Industry
- Enrollment
- 1,217 participants
Conditions and interventions
Conditions
Interventions
- LY3305677 Drug
- LY3549492 Drug
- LY3841136 Drug
- Placebo Drug
- Tirzepatide Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 16, 2023
- Primary completion
- May 31, 2026
- Completion
- Aug 31, 2026
- Last update posted
- Apr 19, 2026
2023 – 2026
United States locations
- U.S. sites
- 49
- U.S. states
- 22
- U.S. cities
- 47
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| The Institute for Liver Health II dba Arizona Clinical Trials - Mesa | Chandler | Arizona | 85225 | Recruiting |
| HOPE Research Institute | Phoenix | Arizona | 85032 | Recruiting |
| Headlands Research - Scottsdale | Scottsdale | Arizona | 85260 | Recruiting |
| The Institute for Liver Health II dba Arizona Liver Health-Tucson | Tucson | Arizona | 85712 | Recruiting |
| NorCal Medical Research, Inc | Greenbrae | California | 94904 | Recruiting |
| Velocity Clinical Research, Huntington Park | Huntington Park | California | 90255 | Recruiting |
| Peninsula Research Associates | Rolling Hills Estates | California | 90274 | Recruiting |
| Diablo Clinical Research, Inc. | Walnut Creek | California | 94598 | Recruiting |
| Stamford Therapeutics Consortium | Stamford | Connecticut | 06905 | Recruiting |
| Northeast Research Institute (NERI) | Fleming Island | Florida | 32003 | Recruiting |
| Indago Research & Health Center, Inc | Hialeah | Florida | 33012 | Recruiting |
| New Horizon Research Center | Miami | Florida | 33165 | Recruiting |
| Suncoast Clinical Research, Inc. | New Port Richey | Florida | 34652 | Recruiting |
| Charter Research - Winter Park | Orlando | Florida | 32803 | Recruiting |
| Charter Research - Lady Lake | The Villages | Florida | 32162 | Recruiting |
| Pacific Diabetes & Endocrine Center | Honolulu | Hawaii | 96817 | Recruiting |
| Medical Research Partners | Ammon | Idaho | 83406 | Recruiting |
| Great Lakes Clinical Trials - Ravenswood | Chicago | Illinois | 60640 | Recruiting |
| NorthShore University Health System | Skokie | Illinois | 60077 | Recruiting |
| Iowa Diabetes and Endocrinology Research Center | West Des Moines | Iowa | 50266 | Recruiting |
| Cotton O'Neil Diabetes & Endocrinology | Topeka | Kansas | 66606 | Recruiting |
| L-MARC Research Center | Louisville | Kentucky | 40213 | Recruiting |
| Knownwell | Needham | Massachusetts | 02492 | Recruiting |
| Lucida Clinical Trials | New Bedford | Massachusetts | 02740 | Recruiting |
| Headlands Research - Detroit | Southfield | Michigan | 48034 | Recruiting |
| Arcturus Healthcare , PLC, Troy Internal Medicine Research Division | Troy | Michigan | 48098 | Recruiting |
| StudyMetrix Research | City of Saint Peters | Missouri | 63303 | Recruiting |
| Clinvest Headlands Llc | Springfield | Missouri | 65807 | Recruiting |
| Las Vegas Medical Research | Las Vegas | Nevada | 89128 | Recruiting |
| Dent Neurologic Institute | Amherst | New York | 14226 | Recruiting |
| Velocity Clinical Research, Syracuse | East Syracuse | New York | 13057 | Recruiting |
| North Suffolk Neurology | Port Jefferson Station | New York | 11776 | Recruiting |
| Rochester Clinical Research, LLC | Rochester | New York | 14609 | Recruiting |
| Medication Management | Greensboro | North Carolina | 27405 | Recruiting |
| Monroe Biomedical Research | Monroe | North Carolina | 28112 | Recruiting |
| Lucas Research, Inc | Morehead City | North Carolina | 28557 | Recruiting |
| Lucas Research, Inc. | New Bern | North Carolina | 28562 | Recruiting |
| CTI Clinical Research Center | Cincinnati | Ohio | 45212 | Recruiting |
| Tribe Clinical Research, LLC | Greenville | South Carolina | 29607 | Recruiting |
| Quality Medical Research | Nashville | Tennessee | 37211 | Recruiting |
| IMA Clinical Research Austin | Austin | Texas | 78745 | Recruiting |
| Velocity Clinical Research, Dallas | Dallas | Texas | 75230 | Recruiting |
| FutureSearch Trials of Dallas | Dallas | Texas | 75251 | Recruiting |
| PlanIt Research, PLLC | Houston | Texas | 77079 | Recruiting |
| Endeavor Clinical Trials | San Antonio | Texas | 78240 | Recruiting |
| Tekton Research - Fredericksburg Road | San Antonio | Texas | 78258 | Recruiting |
| Texas Valley Clinical Research | Weslaco | Texas | 78596 | Recruiting |
| Sovah Clinical Research-River District | Danville | Virginia | 24541 | Recruiting |
| Central Washington Health Services Association d/b/a Confluence Health | Wenatchee | Washington | 98801 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 4 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06143956, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 19, 2026 · Synced May 6, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06143956 live on ClinicalTrials.gov.