Beamion LUNG-2: A Study to Test Whether Zongertinib (BI 1810631) Helps People With Advanced Non-small Cell Lung Cancer With HER2 Mutations Compared With Standard Treatment
Public ClinicalTrials.gov record NCT06151574. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Beamion LUNG 2: A Phase III, Open-label, Randomized, Active-controlled, Multi-centre Trial Evaluating Orally Administered Zongertinib (BI 1810631) Compared With Standard of Care as First-line Treatment in Patients With Unresectable, Locally Advanced or Metastatic Non-squamous Non-small Cell Lung Cancer Harbouring HER2 Tyrosine Kinase Domain Mutations
Study identification
- NCT ID
- NCT06151574
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Boehringer Ingelheim
- Industry
- Enrollment
- 428 participants
Conditions and interventions
Conditions
Interventions
- carboplatin Drug
- cisplatin Drug
- pembrolizumab Drug
- pemetrexed Drug
- zongertinib Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 8, 2024
- Primary completion
- Sep 1, 2026
- Completion
- Jan 27, 2028
- Last update posted
- Apr 28, 2026
2024 – 2028
United States locations
- U.S. sites
- 22
- U.S. states
- 13
- U.S. cities
- 22
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Clearview Cancer Institute | Huntsville | Alabama | 35805 | — |
| Pioneer Research Center - Bullhead City | Bullhead City | Arizona | 86442 | — |
| Precision NextGen Oncology | Beverly Hills | California | 90212 | — |
| ClinRé 001-022 (Premier Cancer Care and Infusion Center) | Fresno | California | 93710 | — |
| OPN Healthcare, Inc. | Glendale | California | 91203 | — |
| Scripps Green Hospital | La Jolla | California | 92037 | — |
| Valkyrie Clinical Trials | Los Angeles | California | 90067 | — |
| Sharp Memorial Hospital | San Diego | California | 92123 | — |
| St. Louis Cancer Care, LLP | Bridgeton | Missouri | 63044 | — |
| Oncology Hematology Associates | Springfield | Missouri | 65807 | — |
| Cancer Care Specialists | Reno | Nevada | 89511 | — |
| Northwell Health | Lake Success | New York | 11042 | — |
| Montefiore Medical Center | The Bronx | New York | 10461 | — |
| Regional Medical Oncology Center | Wilson | North Carolina | 27893 | — |
| Gabrail Cancer Center | Canton | Ohio | 44718 | — |
| Carolina Blood and Cancer Care Associates, PA | Rock Hill | South Carolina | 29732 | — |
| SCRI Oncology Partners | Nashville | Tennessee | 37203 | — |
| Huntsman Cancer Institute | Salt Lake City | Utah | 84112 | — |
| Virginia Cancer Specialists, PC | Fairfax | Virginia | 22031 | — |
| Swedish Cancer Institute | Edmonds | Washington | 98026 | — |
| Swedish Cancer Institute | Issaquah | Washington | 98029 | — |
| Swedish Cancer Institute | Seattle | Washington | 98104 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 140 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06151574, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 28, 2026 · Synced Apr 29, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06151574 live on ClinicalTrials.gov.