ClinicalTrials.gov record
Recruiting Phase 1 Interventional

A Study to Assess BMS-986453 in Participants With Relapsed and/or Refractory Multiple Myeloma

ClinicalTrials.gov ID: NCT06153251

Public ClinicalTrials.gov record NCT06153251. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Apr 23, 2026, 12:16 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1, Open-Label, Dose-Finding Study of BMS-986453, Dual Targeting BCMAxGPRC5D Chimeric Antigen Receptor T Cells, in Participants With Relapsed and/or Refractory Multiple Myeloma

Study identification

NCT ID
NCT06153251
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 1
Lead sponsor
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
Industry
Enrollment
187 participants

Conditions and interventions

Interventions

  • BMS-986453 Drug
  • Cyclophosphamide Drug
  • Fludarabine Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 22, 2024
Primary completion
May 1, 2030
Completion
May 1, 2030
Last update posted
Mar 17, 2026

2024 – 2030

United States locations

U.S. sites
13
U.S. states
9
U.S. cities
11
Facility City State ZIP Site status
University of Alabama at Birmingham Birmingham Alabama 35294 Recruiting
City of Hope Comprehensive Cancer Center Duarte California 91010 Recruiting
UCSF Helen Diller Medical Center at Parnassus Heights San Francisco California 94143 Recruiting
Stanford University Medical Center Stanford California 94305 Recruiting
Colorado Blood Cancer Institute Denver Colorado 80218 Recruiting
Yale Cancer Center New Haven Connecticut 06520 Recruiting
Moffitt Cancer Center Tampa Florida 33612 Recruiting
Dana-Farber Cancer Institute Boston Massachusetts 02215 Recruiting
Icahn School of Medicine at Mount Sinai New York New York 10029 Recruiting
Memorial Sloan Kettering Cancer Center New York New York 10065 Recruiting
Local Institution - 0008 Nashville Tennessee 37203 Not yet recruiting
Tennessee Oncology Nashville Tennessee 37203 Recruiting
Swedish Medical Center Seattle Washington 98104 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 6 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06153251, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 17, 2026 · Synced Apr 23, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06153251 live on ClinicalTrials.gov.

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