Study Assessing Activity of Intravenous (IV) Etentamig Monotherapy Versus Standard Available Therapies in Adult Participants With Relapsed or Refractory Multiple Myeloma

ClinicalTrials.gov ID: NCT06158841

Public ClinicalTrials.gov record NCT06158841. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 5, 2026, 7:26 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3, Multicenter, Randomized, Open Label Study of Etentamig Compared With Standard Available Therapies in Subjects With Relapsed or Refractory Multiple Myeloma (3L+ RRMM Monotherapy Study)

Study identification

NCT ID: NCT06158841
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 3
Lead sponsor: AbbVie; Industry
Enrollment: 380 participants

Conditions and interventions

Conditions

Multiple Myeloma

Interventions

Bortezomib Drug
Carfilzomib Drug
Dexamethasone Drug
Elotuzumab Drug
Etentamig Drug
Pomalidomide Drug
Selinexor Drug

Drug

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: May 18, 2024
Primary completion: Nov 30, 2027
Completion: Nov 30, 2027
Last update posted: Mar 12, 2026

2024 – 2027

United States locations

U.S. sites: 46
U.S. states: 23
U.S. cities: 40

Facility	City	State	ZIP	Site status
University of Alabama at Birmingham - Main /ID# 261434	Birmingham	Alabama	35233	Recruiting
Mayo Clinic Hospital - Phoenix /ID# 263326	Phoenix	Arizona	85054	Recruiting
Alta Bates Summit Medical Center for Research /ID# 261438	Berkeley	California	94705	Completed
Providence - St. Jude Medical Center /ID# 262031	Fullerton	California	92835	Recruiting
VA Loma Linda Healthcare System /ID# 261015	Loma Linda	California	92357	Recruiting
Cedars-Sinai Medical Center /ID# 261008	Los Angeles	California	90048	Recruiting
Rocky Mountain Cancer Centers - Lone Tree /ID# 278320	Lone Tree	Colorado	80124	Recruiting
Mayo Clinic Hospital Jacksonville /ID# 263324	Jacksonville	Florida	32224	Recruiting
Cancer Specialists of North Florida - Jacksonville - AC Skinner Parkway /ID# 246230	Jacksonville	Florida	32256	Recruiting
Winship Cancer Institute of Emory University /ID# 262525	Atlanta	Georgia	30322	Recruiting
University of Illinois Hospital and Health Sciences System /ID# 246349	Chicago	Illinois	60607	Recruiting
Rush University Medical Center /ID# 265690	Chicago	Illinois	60612	Recruiting
Nancy W. Knowles Cancer Center /ID# 271361	Elmhurst	Illinois	60126	Recruiting
Springfield Clinic - First /ID# 262266	Springfield	Illinois	62702	Recruiting
Our Lady Of The Lake Regional Medical Center /ID# 272780	Baton Rouge	Louisiana	70808	Recruiting
Center for Cancer and Blood Disorders-American Oncology Partners of Maryland /ID# 263637	Bethesda	Maryland	20817	Recruiting
Beth Israel Deaconess Medical Center /ID# 271535	Boston	Massachusetts	02215	Recruiting
Dana-Farber Cancer Institute /ID# 261554	Boston	Massachusetts	02215	Recruiting
Regents of the University of Michigan /ID# 261577	Ann Arbor	Michigan	48109-1276	Recruiting
Karmanos Cancer Institute - Detroit /ID# 266298	Detroit	Michigan	48201	Recruiting
Henry Ford Hospital /ID# 262704	Detroit	Michigan	48202	Recruiting
Barbara Ann Karmanos Cancer Institute - McLaren Greater Lansing /ID# 259891	Lansing	Michigan	48912	Recruiting
Mayo Clinic - Rochester /ID# 246228	Rochester	Minnesota	55905-0001	Recruiting
University of Missouri Hospital /ID# 261553	Columbia	Missouri	65212	Recruiting
Nebraska Cancer Specialists - Omaha - Wright Street /ID# 276772	Omaha	Nebraska	68130	Recruiting
New York Cancer & Blood Specialists - Bay Shore /ID# 261524	Bay Shore	New York	11706	Recruiting
New York Cancer & Blood Specialists - Lake Success Medical Oncology /ID# 262953	New Hyde Park	New York	11042	Completed
New York Cancer and Blood Specialists - New York /ID# 262951	New York	New York	10028	Completed
Eastchester Center for Cancer Care /ID# 262952	The Bronx	New York	10469	Recruiting
University of North Carolina /ID# 259854	Chapel Hill	North Carolina	27514	Recruiting
Atrium Health Levine Cancer Institute /ID# 246199	Charlotte	North Carolina	28204	Recruiting
Duke University Medical Center /ID# 259694	Durham	North Carolina	27710	Recruiting
University Of Cincinnati Medical Center /ID# 246415	Cincinnati	Ohio	45219	Recruiting
Cleveland Clinic Main Campus /ID# 246183	Cleveland	Ohio	44195	Recruiting
Oregon Medical Research Center /ID# 262335	Portland	Oregon	97239	Recruiting
Medical University of South Carolina /ID# 259692	Charleston	South Carolina	29425	Recruiting
University of Tennessee Health Science Center /ID# 261622	Memphis	Tennessee	38103	Recruiting
Baptist Memorial Hospital /ID# 270910	Memphis	Tennessee	38120	Recruiting
The West Clinic /ID# 262444	Memphis	Tennessee	38120	Recruiting
Vanderbilt University Medical Center /ID# 261621	Nashville	Tennessee	37232-0011	Recruiting
Oncology Consultants /ID# 276774	Houston	Texas	77030	Recruiting
Texas Oncology - Northeast Texas /ID# 278304	Tyler	Texas	75702	Recruiting
Virginia Cancer Specialists - Fairfax /ID# 262792	Fairfax	Virginia	22031	Recruiting
Virginia Oncology Associates - Norfolk (Lake Wright) /ID# 278314	Norfolk	Virginia	23502	Recruiting
VCU Massey Cancer Center: Dalton Oncology Clinic /ID# 261944	Richmond	Virginia	23298	Recruiting
Northwest Medical Specialties Tacoma /ID# 276281	Tacoma	Washington	98405	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 120 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT06158841, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Mar 12, 2026 · Synced May 5, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06158841 live on ClinicalTrials.gov.

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