ClinicalTrials.gov record
A Study Evaluating Efruxifermin in Subjects With Non-invasively Diagnosed Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Nonalcoholic Fatty Liver Disease (NAFLD)/Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
ClinicalTrials.gov ID: NCT06161571
Public ClinicalTrials.gov record NCT06161571. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 20, 2026, 11:20 AM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of Efruxifermin in Subjects With Non-invasively Diagnosed Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Nonalcoholic Fatty Liver Disease (NAFLD)/Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
Study identification
- NCT ID
- NCT06161571
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Akero Therapeutics, Inc
- Industry
- Enrollment
- 700 participants
Conditions and interventions
Conditions
Interventions
- Efruxifermin Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 9, 2023
- Primary completion
- Mar 2, 2026
- Completion
- Jun 18, 2026
- Last update posted
- Apr 29, 2026
2023 – 2026
United States locations
- U.S. sites
- 139
- U.S. states
- 28
- U.S. cities
- 120
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Akero Clinical Study Site | Birmingham | Alabama | 35209 | — |
| Akero Clinical Study Site | Chandler | Arizona | 85224 | — |
| Akero Clinical Study Site | Flagstaff | Arizona | 86001 | — |
| Akero Clinical Study Site | Peoria | Arizona | 85381 | — |
| Akero Clinical Study Site | Tucson | Arizona | 85712 | — |
| Akero Clinical Study Site | Tucson | Arizona | 85715 | — |
| Akero Clinical Study Site | Conway | Arkansas | 72032 | — |
| Akero Clinical Study Site | Jonesboro | Arkansas | 72401 | — |
| Akero Clinical Study Site | Little Rock | Arkansas | 72205 | — |
| Akero Clinical Study Site | North Little Rock | Arkansas | 72117 | — |
| Akero Clinical Study Site | Chula Vista | California | 91910 | — |
| Akero Clinical Study Site | Coronado | California | 92118 | — |
| Akero Clinical Study Site | Cypress | California | 90630 | — |
| Akero Clinical Study Site | Inglewood | California | 90301 | — |
| Akero Clinical Study Site | La Mesa | California | 91942 | — |
| Akero Clinical Study Site | Lancaster | California | 93534 | — |
| Akero Clinical Study Site | Los Angeles | California | 90036-4669 | — |
| Akero Clinical Study Site | Los Angeles | California | 90057 | — |
| Akero Clinical Study Site | Palm Springs | California | 92262 | — |
| Akero Clinical Study Site | San Diego | California | 92120 | — |
| Akero Clinical Study Site | San Diego | California | 92123 | — |
| Akero Clinical Study Site | San Francisco | California | 94115 | — |
| Akero Clinical Study Site | Santa Maria | California | 93458 | — |
| Akero Clinical Study Site | Englewood | Colorado | 80113 | — |
| Akero Clinical Study Site | Bradenton | Florida | 34208 | — |
| Akero Clinical Study Site | Brandon | Florida | 33511 | — |
| Akero Clinical Study Site | Fort Myers | Florida | 33912 | — |
| Akero Clinical Study Site | Gainesville | Florida | 32610 | — |
| Akero Clinical Study Site | Hialeah Gardens | Florida | 33016 | — |
| Akero Clinical Study Site | Inverness | Florida | 34452 | — |
| Akero Clinical Study Site | Jacksonville | Florida | 32256 | — |
| Akero Clinical Study Site | Lady Lake | Florida | 32159 | — |
| Akero Clinical Study Site | Lakewood Rch | Florida | 34211 | — |
| Akero Clinical Study Site | Largo | Florida | 33777 | — |
| Akero Clinical Study Site | Maitland | Florida | 32751 | — |
| Akero Clinical Study Site | Miami | Florida | 33136 | — |
| Akero Clinical Study Site | Miami Lakes | Florida | 33016 | — |
| Akero Clinical Study Site | Naples | Florida | 34102 | — |
| Akero Clinical Study Site | Ocala | Florida | 34471 | — |
| Akero Clinical Study Site | Port Orange | Florida | 32127 | — |
| Akero Clinical Study Site | Sarasota | Florida | 34240 | — |
| Akero Clinical Study Site | The Villages | Florida | 32162 | — |
| Akero Clinical Study Site | Venice | Florida | 34285 | — |
| Akero Clinical Study Site | Viera | Florida | 32940 | — |
| Akero Clinical Study Site | West Palm Beach | Florida | 33401 | — |
| Akero Clinical Study Site | Winter Park | Florida | 32789 | — |
| Akero Clinical Study Site | Winter Park | Florida | 32792 | — |
| Akero Clinical Study Site | Columbus | Georgia | 31904 | — |
| Akero Clinical Study Site | Gainesville | Georgia | 30501 | — |
| Akero Clinical Study Site | Marietta | Georgia | 30060 | — |
| Akero Clinical Study Site | South Bend | Indiana | 46635 | — |
| Akero Clinical Study Site | West Des Moines | Iowa | 50265 | — |
| Akero Clinical Study Site | Topeka | Kansas | 66606 | — |
| Akero Clinical Study Site | Wichita | Kansas | 67205 | — |
| Akero Clinical Study Site | Bastrop | Louisiana | 71220 | — |
| Akero Clinical Study Site | Covington | Louisiana | 70433 | — |
| Akero Clinical Study Site | Houma | Louisiana | 70363 | — |
| Akero Clinical Study Site | Marrero | Louisiana | 70072 | — |
| Akero Clinical Study Site | Metairie | Louisiana | 70006 | — |
| Akero Clinical Study Site | New Orleans | Louisiana | 70121 | — |
| Akero Clinical Study Site | Shreveport | Louisiana | 71103 | — |
| Akero Clinical Study Site | Baltimore | Maryland | 21202 | — |
| Akero Clinical Study Site | Glen Burnie | Maryland | 21061 | — |
| Akero Clinical Study Site | Greenbelt | Maryland | 20770 | — |
| Akero Clinical Study Site | South Dartmouth | Massachusetts | 02747 | — |
| Akero Clinical Study Site | Southfield | Michigan | 48075 | — |
| Akero Clinical Study Site | Wyoming | Michigan | 49519 | — |
| Akero Clinical Study Site | Ypsilanti | Michigan | 48197 | — |
| Akero Clinical Study Site | Columbia | Missouri | 65201 | — |
| Akero Clinical Study Site | Kansas City | Missouri | 64131 | — |
| Akero Clinical Study Site | Las Vegas | Nevada | 89106 | — |
| Akero Clinical Study Site | Las Vegas | Nevada | 89109 | — |
| Akero Clinical Study Site | Reno | Nevada | 89511 | — |
| Akero Clinical Study Site | Brick | New Jersey | 08724 | — |
| Akero Clinical Study Site | Florham Park | New Jersey | 07932 | — |
| Akero Clinical Study Site | Somers Point | New Jersey | 08244 | — |
| Akero Clinical Study Site | Sparta | New Jersey | 07871 | — |
| Akero Clinical Study Site | Santa Fe | New Mexico | 87505 | — |
| Akero Clinical Study Site | New York | New York | 10029 | — |
| Akero Clinical Study Site | New York | New York | 10033 | — |
| Akero Clinical Study Site | Chapel Hill | North Carolina | 27516 | — |
| Akero Clinical Study Site | Charlotte | North Carolina | 28204 | — |
| Akero Clinical Study Site | Fayetteville | North Carolina | 28304 | — |
| Akero Clinical Study Site | Morehead City | North Carolina | 28557 | — |
| Akero Clinical Study Site | New Bern | North Carolina | 28562 | — |
| Akero Clinical Study Site | Raleigh | North Carolina | 27612 | — |
| Akero Clinical Study Site | Statesville | North Carolina | 28625 | — |
| Akero Clinical Study Site | Columbus | Ohio | 43213 | — |
| Akero Clinical Study Site | Dayton | Ohio | 45414 | — |
| Akero Clinical Study Site | Springboro | Ohio | 45066 | — |
| Akero Clinical Study Site | Westlake | Ohio | 44145 | — |
| Akero Clinical Study Site | Philadelphia | Pennsylvania | 19104 | — |
| Akero Clinical Study Site | Philadelphia | Pennsylvania | 19107 | — |
| Akero Clinical Study Site | Pittsburgh | Pennsylvania | 15213 | — |
| Akero Clinical Study Site | Columbia | South Carolina | 29204 | — |
| Akero Clinical Study Site | Summerville | South Carolina | 29485 | — |
| Akero Clinical Study Site | Chattanooga | Tennessee | 37421 | — |
| Akero Clinical Study Site | Clarksville | Tennessee | 37040 | — |
| Akero Clinical Study Site | Hermitage | Tennessee | 37076 | — |
| Akero Clinical Study Site | Nashville | Tennessee | 37211 | — |
| Akero Clinical Study Site | Amarillo | Texas | 79106 | — |
| Akero Clinical Study Site | Austin | Texas | 78745 | — |
| Akero Clinical Study Site | Austin | Texas | 78757 | — |
| Akero Clinical Study Site | Bellaire | Texas | 77401 | — |
| Akero Clinical Study Site | Brownsville | Texas | 78520 | — |
| Akero Clinical Study Site | Corpus Christi | Texas | 78404 | — |
| Akero Clinical Study Site | Dallas | Texas | 75203 | — |
| Akero Clinical Study Site | Dallas | Texas | 75230 | — |
| Akero Clinical Study Site | Dallas | Texas | 75234 | — |
| Akero Clinical Study Site | Dallas | Texas | 75390 | — |
| Akero Clinical Study Site | Edinburg | Texas | 78539 | — |
| Akero Clinical Study Site | Fort Worth | Texas | 76104 | — |
| Akero Clinical Study Site | Houston | Texas | 77030 | — |
| Akero Clinical Study Site | Houston | Texas | 77079 | — |
| Akero Clinical Study Site | Houston | Texas | 77084 | — |
| Akero Clinical Study Site | Lewisville | Texas | 75057 | — |
| Akero Clinical Study Site | McAllen | Texas | 78504 | — |
| Akero Clinical Study Site | San Antonio | Texas | 78215 | — |
| Akero Clinical Study Site | San Antonio | Texas | 78222 | — |
| Akero Clinical Study Site | San Antonio | Texas | 78229 | — |
| Akero Clinical Study Site | San Antonio | Texas | 78258 | — |
| Akero Clinical Study Site | San Marcos | Texas | 78666-7502 | — |
| Akero Clinical Study Site | Waco | Texas | 76710 | — |
| Akero Clinical Study Site | Webster | Texas | 77598 | — |
| Akero Clinical Study Site | Wichita Falls | Texas | 76301 | — |
| Akero Clinical Study Site | Ogden | Utah | 84405 | — |
| Akero Clinical Study Site | Salt Lake City | Utah | 84117 | — |
| Akero Clinical Study Site | Sandy City | Utah | 84092 | — |
| Akero Clinical Study Site | South Ogden | Utah | 84405 | — |
| Akero Clinical Study Site | Falls Church | Virginia | 22042-3300 | — |
| Akero Clinical Study Site | Norfolk | Virginia | 23502 | — |
| Akero Clinical Study Site | Richmond | Virginia | 23226 | — |
| Akero Clinical Study Site | Richmond | Virginia | 23236 | — |
| Akero Clinical Study Site | Richmond | Virginia | 23249 | — |
| Akero Clinical Study Site | Richmond | Virginia | 23298 | — |
| Akero Clinical Study Site | Roanoke | Virginia | 24014 | — |
| Akero Clinical Study Site | Suffolk | Virginia | 23435 | — |
| Akero Clinical Study Site | Seattle | Washington | 98105 | — |
| Akero Clinical Study Site | Spokane | Washington | 99218 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 72 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06161571, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 29, 2026 · Synced May 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06161571 live on ClinicalTrials.gov.