A Clinical Study of MK-4208/TERN-701 in Participants With Chronic Myeloid Leukemia (CML) (MK-4208-003/Tern701-1012/CARDINAL)
Public ClinicalTrials.gov record NCT06163430. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1/2 Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of TERN-701 in Participants With Chronic Myeloid Leukemia
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Researchers are looking for a new way to treat a blood cancer called chronic myeloid leukemia (CML). Researchers want to learn if MK-4208 (Tern-701) can treat this type of blood cancer. The goal of this study is to learn about the safety of different doses (amounts) of MK-4208 (Tern-701) and if people tolerate them. Researchers also want to find the highest dose of MK-4208 (Tern-701) that people can tolerate and may work to treat blood cancer.
Study identification
- NCT ID
- NCT06163430
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Enrollment
- 330 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 26, 2024 (Actual)
- Primary completion
- Nov 30, 2029 (Estimated)
- Completion
- May 31, 2030 (Estimated)
- Last update posted
- Oct 15, 2026
2024 – 2030
United States locations
- U.S. sites
- 18
- U.S. states
- 14
- U.S. cities
- 18
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama Medicine (UAB Medicine) | Birmingham | Alabama | 35233 | Recruiting |
| Banner MD Anderson Cancer Center | Gilbert | Arizona | 85234 | Recruiting |
| UC Irvine Health | Orange | California | 92868 | Recruiting |
| Rocky Mountain Cancer Centers, LLP | Lone Tree | Colorado | 80303 | Recruiting |
| Florida Cancer Specialists - South Region Research Office | Fort Myers | Florida | 33901 | Not yet recruiting |
| Florida Cancer Affiliates - Ocala | Ocala | Florida | 34474 | Recruiting |
| Florida Cancer Specialists - North Region Research Office | St. Petersburg | Florida | 33705 | Not yet recruiting |
| Florida Cancer Specialists - East Region Research Office | West Palm Beach | Florida | 33401 | Not yet recruiting |
| Georgia Cancer Center at Augusta University | Augusta | Georgia | 30912 | Recruiting |
| Memorial Sloan Kettering Cancer Center - Main Campus | New York | New York | 10065 | Recruiting |
| Atrium Health Levine Cancer Institute | Winston-Salem | North Carolina | 27103 | Recruiting |
| Willamette Valley Cancer Institute and Research Center | Eugene | Oregon | 97401 | Recruiting |
| Oregon Health & Science University | Portland | Oregon | 97239 | Recruiting |
| Thomas Jefferson University - Center City (Philadelphia) | Philadelphia | Pennsylvania | 19107 | Recruiting |
| Tristar BMT | Nashville | Tennessee | 37203 | Recruiting |
| The University of Texas M.D. Anderson Cancer Center | Houston | Texas | 77030 | Recruiting |
| Huntsman Cancer Institute | Salt Lake City | Utah | 84112 | Recruiting |
| Fred Hutchinson Cancer Center | Seattle | Washington | 98109 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 36 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06163430, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 15, 2026 · Synced Oct 19, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06163430 live on ClinicalTrials.gov.