A Study of VERVE-102 in Patients With Familial Hypercholesterolemia or Premature Coronary Artery Disease

ClinicalTrials.gov ID: NCT06164730

Public ClinicalTrials.gov record NCT06164730. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 21, 2026, 1:01 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Open-label, Phase 1b, Single Ascending Dose Study to Evaluate the Safety of VERVE-102 Administered to Patients With Heterozygous Familial Hypercholesterolemia or Premature Coronary Artery Disease Who Require Additional Lowering of Low-density Lipoprotein Cholesterol

Study identification

NCT ID: NCT06164730
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 1
Lead sponsor: Verve Therapeutics, Inc.; Industry
Enrollment: 85 participants

Conditions and interventions

Conditions

Interventions

VERVE-102 Drug

Drug

Eligibility (public fields only)

Age range: 18 Years to 70 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Apr 29, 2024
Primary completion: Jul 31, 2026
Completion: Jul 31, 2027
Last update posted: Mar 31, 2026

2024 – 2027

United States locations

U.S. sites: 8
U.S. states: 6
U.S. cities: 8

Facility	City	State	ZIP	Site status
Clinical Study Center	Dothan	Alabama	36305	Recruiting
Clinical Study Center	Pomona	California	91768	Recruiting
Clinical Study Center	Boca Raton	Florida	33434	Recruiting
Clinical Study Center	Jacksonville	Florida	32216	Recruiting
Clinical Study Center	Winter Park	Florida	32789	Recruiting
Clinical Study Center	High Point	North Carolina	27260	Recruiting
Clinical Study Center	DeSoto	Texas	75115	Recruiting
Clinical Study Center	Renton	Washington	98057	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 14 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT06164730, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Mar 31, 2026 · Synced May 21, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06164730 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →