A Trial to Learn if Fianlimab and Cemiplimab Are Safe and Work Better Than Anti-PD1 Alone in Adult Participants With Resectable Stage 3 or 4 Melanoma
Public ClinicalTrials.gov record NCT06190951. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2 Peri-operative Trial of Fianlimab and Cemiplimab Compared With Anti-PD1 Alone in Patients With Resectable Stage III and IV Melanoma
Study identification
- NCT ID
- NCT06190951
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Regeneron Pharmaceuticals
- Industry
- Enrollment
- 151 participants
Conditions and interventions
Conditions
Interventions
- Fixed Dose Combination (FDC) cemiplimab+fianlimab Drug
- Placebo Drug
- cemiplimab Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Not listed
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 17, 2024
- Primary completion
- Nov 1, 2026
- Completion
- Dec 8, 2030
- Last update posted
- Feb 9, 2026
2024 – 2030
United States locations
- U.S. sites
- 28
- U.S. states
- 15
- U.S. cities
- 25
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| UC San Diego | La Jolla | California | 92093 | — |
| USC Norris Comprehensive Cancer Center | Los Angeles | California | 90089 | — |
| Hoag Family Cancer Institute | Newport Beach | California | 92663 | — |
| California Pacific Medical Center Research Institute | San Francisco | California | 94115 | — |
| University of California San Francisco (UCSF) | San Francisco | California | 94143 | — |
| St John's Cancer Institute | Santa Monica | California | 90404 | — |
| University of Colorado Cancer Center | Aurora | Colorado | 80045 | — |
| Hartford Hospital | Hartford | Connecticut | 06102 | — |
| Yale University Cancer Center | New Haven | Connecticut | 06510 | — |
| Emory Healthcare, Emory Clinic | Atlanta | Georgia | 30322 | — |
| NorthShore University HealthSystem | Evanston | Illinois | 60201 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Dana Farber Cancer Institute Brookline Avenue | Boston | Massachusetts | 02215 | — |
| University of Massachusetts Chan Medical School | Worcester | Massachusetts | 01655 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Rutgers Cancer Institute of New Jersey | New Brunswick | New Jersey | 08901 | — |
| Northwell Health Cancer Institute | Lake Success | New York | 11042 | — |
| Duke Cancer Institute, University Hospital | Durham | North Carolina | 27710 | — |
| Seidman Cancer Center | Cleveland | Ohio | 44106 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| The Ohio State University James Comprehensive Cancer Center | Columbus | Ohio | 43210 | — |
| Thomas Jefferson University Hospital | Philadelphia | Pennsylvania | 19107 | — |
| University of Pittsburgh | Pittsburgh | Pennsylvania | 15232 | — |
| University of Tennessee Medical Center | Knoxville | Tennessee | 37920 | — |
| UT Southwestern/Simmons Comprehensive Cancer Center | Dallas | Texas | 75235 | — |
| University of Texas MD Anderson Cancer Center | Houston | Texas | 77030 | — |
| University of Virginia | Charlottesville | Virginia | 22908 | — |
| Inova Schar Cancer Institute | Fairfax | Virginia | 22031 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 76 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06190951, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 9, 2026 · Synced Apr 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06190951 live on ClinicalTrials.gov.