A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation

ClinicalTrials.gov ID: NCT06200207

Public ClinicalTrials.gov record NCT06200207. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Apr 22, 2026, 8:43 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Effects of Ziltivekimab Versus Placebo on Heart Failure Symptoms and Physical Function in Patients With Heart Failure With Mildly Reduced or Preserved Ejection Fraction and Systemic Inflammation

Study identification

NCT ID: NCT06200207
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 3
Lead sponsor: Novo Nordisk A/S; Industry
Enrollment: 680 participants

Conditions and interventions

Conditions

Interventions

Placebo Drug
Ziltivekimab Drug

Drug

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Not listed

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Mar 31, 2024
Primary completion: Sep 30, 2026
Completion: Jan 7, 2027
Last update posted: Apr 6, 2026

2024 – 2027

United States locations

U.S. sites: 37
U.S. states: 16
U.S. cities: 36

Facility	City	State	ZIP	Site status
Advanced Cardiovascular, LLC	Alexander City	Alabama	35010	Completed
Eastern Shore Rsrch Inst, LLC	Fairhope	Alabama	36532	Active, not recruiting
Cardiology & Medicine Clinic	Little Rock	Arkansas	72204	Completed
Valley Clinical Trials, Inc.	Northridge	California	91325	Recruiting
UCI Health	Orange	California	92868	Completed
South California Heart Spc	Pasadena	California	91105	Active, not recruiting
Clearwater Cardiovascular Consultants	Largo	Florida	33777	Recruiting
Ocala Cardiovascular Research	Ocala	Florida	34471	Active, not recruiting
Ormond Beach Clinical Research	Ormond Beach	Florida	32174	Active, not recruiting
St Johns Ctr Clin Rsch-St. Aug	Saint Augustine	Florida	32086	Active, not recruiting
GA Arrhythmia Cons & Rsch Inst	Macon	Georgia	31201	Active, not recruiting
Velocity Clin Rsrch - Savannah	Savannah	Georgia	31406	Completed
Chicago Medical Research LLC	Hazel Crest	Illinois	60429	Completed
UofL Health Care Outpatient	Louisville	Kentucky	40202	Active, not recruiting
Maryland Cardiovascular Specialists - Baltimore	Baltimore	Maryland	21229	Completed
MD Medical Research	Oxon Hill	Maryland	20745	Completed
Cardio and Vascular Assoc-CAVA	Bloomfield Hills	Michigan	48304	Active, not recruiting
Millennium Cardiology	Farmington Hills	Michigan	48334	Active, not recruiting
Kansas City VA Medical Center	Kansas City	Missouri	64128	Recruiting
Washington University	St Louis	Missouri	63110	Active, not recruiting
Renown Regional Medical Center	Reno	Nevada	89502	Active, not recruiting
Long Island Cardiovascular Consultants PC	Lake Success	New York	11042	Completed
Mount Sinai Hosp at NYC	New York	New York	10019	Active, not recruiting
Northwell Health Phys Cardio	Riverhead	New York	11901	Active, not recruiting
University Of North Carolina At Chapel Hill	Chapel Hill	North Carolina	27599-7046	Active, not recruiting
AMS Cardiology	Horsham	Pennsylvania	19044	Active, not recruiting
Univ of Pennsylvania Hospital	Philadelphia	Pennsylvania	19104	Active, not recruiting
PharmaTex Research	Amarillo	Texas	79106	Recruiting
University of Texas Southwestern Medical Center	Dallas	Texas	75390-9302	Active, not recruiting
David Turbay, MD, PLLC	El Paso	Texas	79905	Active, not recruiting
Private Practice Leadership LLC.	Katy	Texas	77493	Completed
Clinical Advancement Center	San Antonio	Texas	78212	Active, not recruiting
Clinical Advancement Ctr, PLLC	San Antonio	Texas	78212	Not yet recruiting
Sherman Clinical Research	Sherman	Texas	75090	Active, not recruiting
Northwest Heart Center	Tomball	Texas	77375	Active, not recruiting
Sentara Health Research Center	Norfolk	Virginia	23507	Completed
Virginia Commonwealth University	Richmond	Virginia	23219	Completed

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 178 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT06200207, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Apr 6, 2026 · Synced Apr 22, 2026

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The complete protocol, eligibility criteria, and contact information for NCT06200207 live on ClinicalTrials.gov.

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