A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation
Public ClinicalTrials.gov record NCT06200207. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Effects of Ziltivekimab Versus Placebo on Heart Failure Symptoms and Physical Function in Patients With Heart Failure With Mildly Reduced or Preserved Ejection Fraction and Systemic Inflammation
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The study is being done to see if ziltivekimab can be used to treat participants living with heart failure and inflammation. Participants will either get ziltivekimab (active medicine) or placebo (inactive substance that looks like the study medicine but does not contain any medicine). The treatment participants get is decided by chance. Participant's chance of getting ziltivekimab or placebo is the same. Ziltivekimab is not yet approved in any country or region in the world. It is a new medicine that doctors cannot prescribe. The study is expected to last for up to 1 year and 4 months.
Study identification
- NCT ID
- NCT06200207
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 680 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 31, 2024
- Primary completion
- Sep 30, 2026
- Completion
- Jan 7, 2027
- Last update posted
- Aug 31, 2026
2024 – 2027
United States locations
- U.S. sites
- 37
- U.S. states
- 16
- U.S. cities
- 36
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Advanced Cardiovascular, LLC | Alexander City | Alabama | 35010 | — |
| Eastern Shore Rsrch Inst, LLC | Fairhope | Alabama | 36532 | — |
| Cardiology & Medicine Clinic | Little Rock | Arkansas | 72204 | — |
| Valley Clinical Trials, Inc. | Northridge | California | 91325 | — |
| UCI Health | Orange | California | 92868 | — |
| South California Heart Spc | Pasadena | California | 91105 | — |
| Clearwater Cardiovascular Consultants | Largo | Florida | 33777 | — |
| Ocala Cardiovascular Research | Ocala | Florida | 34471 | — |
| Ormond Beach Clinical Research | Ormond Beach | Florida | 32174 | — |
| St Johns Ctr Clin Rsch-St. Aug | Saint Augustine | Florida | 32086 | — |
| GA Arrhythmia Cons & Rsch Inst | Macon | Georgia | 31201 | — |
| Velocity Clin Rsrch - Savannah | Savannah | Georgia | 31406 | — |
| Chicago Medical Research LLC | Hazel Crest | Illinois | 60429 | — |
| UofL Health Care Outpatient | Louisville | Kentucky | 40202 | — |
| Maryland Cardiovascular Specialists - Baltimore | Baltimore | Maryland | 21229 | — |
| MD Medical Research | Oxon Hill | Maryland | 20745 | — |
| Cardio and Vascular Assoc-CAVA | Bloomfield Hills | Michigan | 48304 | — |
| Millennium Cardiology | Farmington Hills | Michigan | 48334 | — |
| Kansas City VA Medical Center | Kansas City | Missouri | 64128 | — |
| Washington University | St Louis | Missouri | 63110 | — |
| Renown Regional Medical Center | Reno | Nevada | 89502 | — |
| Long Island Cardiovascular Consultants PC | Lake Success | New York | 11042 | — |
| Mount Sinai Hosp at NYC | New York | New York | 10019 | — |
| Northwell Health Phys Cardio | Riverhead | New York | 11901 | — |
| University Of North Carolina At Chapel Hill | Chapel Hill | North Carolina | 27599-7046 | — |
| AMS Cardiology | Horsham | Pennsylvania | 19044 | — |
| Univ of Pennsylvania Hospital | Philadelphia | Pennsylvania | 19104 | — |
| PharmaTex Research | Amarillo | Texas | 79106 | — |
| University of Texas Southwestern Medical Center | Dallas | Texas | 75390-9302 | — |
| David Turbay, MD, PLLC | El Paso | Texas | 79905 | — |
| Private Practice Leadership LLC. | Katy | Texas | 77493 | — |
| Clinical Advancement Center | San Antonio | Texas | 78212 | — |
| Clinical Advancement Ctr, PLLC | San Antonio | Texas | 78212 | — |
| Sherman Clinical Research | Sherman | Texas | 75090 | — |
| Northwest Heart Center | Tomball | Texas | 77375 | — |
| Sentara Health Research Center | Norfolk | Virginia | 23507 | — |
| Virginia Commonwealth University | Richmond | Virginia | 23219 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 180 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06200207, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 31, 2026 · Synced Sep 7, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06200207 live on ClinicalTrials.gov.