A Study Comparing Talquetamab Plus Pomalidomide, Talquetamab Plus Teclistamab, and Elotuzumab, Pomalidomide, and Dexamethasone or Pomalidomide, Bortezomib, and Dexamethasone in Participants With Relapsed or Refractory Myeloma Who Have Received an Anti-CD38 Antibody and Lenalidomide
Public ClinicalTrials.gov record NCT06208150. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
64407564MMY3009: A Phase 3 Randomized Study Comparing Talquetamab in Combination With Pomalidomide (Tal-P), Talquetamab in Combination With Teclistamab (Tal-Tec), and Investigator's Choice of Either Elotuzumab, Pomalidomide, and Dexamethasone (EPd) or Pom
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to compare the effectiveness of either talquetamab plus pomalidomide (Tal-P) or talquetamab plus teclistamab (Tal-Tec) with elotuzumab, pomalidomide, and dexamethasone (EPd) or pomalidomide, bortezomib, and dexamethasone (PVd).
Study identification
- NCT ID
- NCT06208150
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 838 participants
Conditions and interventions
Conditions
Interventions
- Talquetamab Drug
- Pomalidomide Drug
- Teclistamab Drug
- Elotuzumab Drug
- Dexamethasone Drug
- Bortezomib Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 22, 2024 (Actual)
- Primary completion
- Apr 1, 2026 (Actual)
- Completion
- Dec 31, 2028 (Estimated)
- Last update posted
- Sep 25, 2026
2024 – 2028
United States locations
- U.S. sites
- 49
- U.S. states
- 27
- U.S. cities
- 44
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| UCSF Fresno | Clovis | California | 93611 | — |
| UCLA | Santa Monica | California | 90404 | — |
| Yale University School Of Medicine | New Haven | Connecticut | 06519 | — |
| Medical Oncology Hematology Consultants, PA | Newark | Delaware | 19713 | — |
| Memorial Healthcare System | Hollywood | Florida | 33021 | — |
| Moffitt Cancer Center | Tampa | Florida | 33612 | — |
| Winship Cancer Institute Emory University | Atlanta | Georgia | 30322 | — |
| City of Hope Cancer Center | Newnan | Georgia | 30265 | — |
| Kootenai Health | Coeur d'Alene | Idaho | 83814 | — |
| Loyola University Medical Center | Maywood | Illinois | 60153 | — |
| University of Iowa Health Care | Waukee | Iowa | 50263 | — |
| Norton Cancer Institute | Louisville | Kentucky | 40207 | — |
| Our Lady of the Lake Hospital | Baton Rouge | Louisiana | 70808 | — |
| Luminis Health Center for Cancer and Blood Disorders | Annapolis | Maryland | 21401 | — |
| University of Maryland School of Medicine | Baltimore | Maryland | 21201 | — |
| The Sidney Kimmel Comprehensive Cancer Center at John Hopkins | Baltimore | Maryland | 21287 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| Henry Ford Cancer Institute | Detroit | Michigan | 48202 | — |
| Henry Ford Health Providence Southfield Hospital | Southfield | Michigan | 48075 | — |
| University Of Minnesota | Minneapolis | Minnesota | 55455 | — |
| Mayo Clinic Rochester | Rochester | Minnesota | 55905 | — |
| Regions Hospital | Saint Paul | Minnesota | 55101 | — |
| University of Nebraska | Omaha | Nebraska | 68105 | — |
| Dartmouth Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | — |
| John Theurer Cancer Center at Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| Roswell Park Cancer Institute | Buffalo | New York | 14263 | — |
| Weill Cornell Medical College | New York | New York | 10065 | — |
| SUNY Upstate Medical University | Syracuse | New York | 13210 | — |
| Duke University Medical Center | Durham | North Carolina | 27705 | — |
| Gabrail Cancer Center | Canton | Ohio | 44718 | — |
| Louis Stokes Cleveland VA Med Ctr | Cleveland | Ohio | 44106 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| Oregon Health And Science University | Portland | Oregon | 97239 | — |
| Penn State Milton S Hershey Medical Ctr | Hershey | Pennsylvania | 17033 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 4215 | — |
| West Penn Hospital | Pittsburgh | Pennsylvania | 15224 | — |
| University Of Pittsburgh Medical Center UPMC Hillman Cancer Center | Pittsburgh | Pennsylvania | 15232 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425-8900 | — |
| Bon Secours Saint Francis Cancer Center | Greenville | South Carolina | 29607 | — |
| UT Southwestern Parkland Hospital | Dallas | Texas | 75390 | — |
| UT Southwestern | Dallas | Texas | 75390 | — |
| Houston Methodist Neal Cancer Center at Texas Medical Center | Houston | Texas | 77030 | — |
| Huntsman Cancer Institute | Salt Lake City | Utah | 84112 | — |
| University of Virginia | Charlottesville | Virginia | 22903 | — |
| Swedish Cancer Institute | Seattle | Washington | 98104 | — |
| Fred Hutchinson Cancer Research Center | Seattle | Washington | 98109 | — |
| NorthWest Medical Specialties, PLLC | Tacoma | Washington | 98405 | — |
| Gundersen Health System | La Crosse | Wisconsin | 54601 | — |
| Medical College Of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 193 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06208150, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 25, 2026 · Synced Oct 18, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06208150 live on ClinicalTrials.gov.