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Recruiting Phase 3 Interventional

A Study Comparing Talquetamab Plus Pomalidomide, Talquetamab Plus Teclistamab, and Elotuzumab, Pomalidomide, and Dexamethasone or Pomalidomide, Bortezomib, and Dexamethasone in Participants With Relapsed or Refractory Myeloma Who Have Received an Anti-CD38 Antibody and Lenalidomide

ClinicalTrials.gov ID: NCT06208150

Public ClinicalTrials.gov record NCT06208150. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 6, 2026, 8:27 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3 Randomized Study Comparing Talquetamab in Combination With Pomalidomide (Tal-P), Talquetamab in Combination With Teclistamab (Tal-Tec), and Investigator's Choice of Either Elotuzumab, Pomalidomide, and Dexamethasone (EPd) or Pomalidomide, Bortezomib, and Dexamethasone (PVd) in Participants With Relapsed or Refractory Myeloma Who Have Received 1 to 4 Prior Lines of Therapy Including an Anti-CD38 Antibody and Lenalidomide

Study identification

NCT ID
NCT06208150
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 3
Lead sponsor
Janssen Research & Development, LLC
Industry
Enrollment
795 participants

Conditions and interventions

Interventions

  • Bortezomib Drug
  • Dexamethasone Drug
  • Elotuzumab Drug
  • Pomalidomide Drug
  • Talquetamab Drug
  • Teclistamab Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 21, 2024
Primary completion
Apr 22, 2026
Completion
Mar 30, 2028
Last update posted
Mar 12, 2026

2024 – 2028

United States locations

U.S. sites
49
U.S. states
27
U.S. cities
44
Facility City State ZIP Site status
UCSF Fresno Clovis California 93611 Recruiting
UCLA Santa Monica California 90404 Recruiting
Yale University School Of Medicine New Haven Connecticut 06519 Recruiting
Medical Oncology Hematology Consultants, PA Newark Delaware 19713 Recruiting
Memorial Healthcare System Hollywood Florida 33021 Recruiting
Moffitt Cancer Center Tampa Florida 33612 Recruiting
Winship Cancer Institute Emory University Atlanta Georgia 30322 Recruiting
City of Hope Cancer Center Newnan Georgia 30265 Recruiting
Kootenai Health Coeur d'Alene Idaho 83814 Completed
Loyola University Medical Center Maywood Illinois 60153 Recruiting
University of Iowa Health Care Waukee Iowa 50263 Recruiting
Norton Cancer Institute Louisville Kentucky 40207 Recruiting
Our Lady of the Lake Hospital Baton Rouge Louisiana 70808 Recruiting
Luminis Health Center for Cancer and Blood Disorders Annapolis Maryland 21401 Completed
University of Maryland School of Medicine Baltimore Maryland 21201 Recruiting
The Sidney Kimmel Comprehensive Cancer Center at John Hopkins Baltimore Maryland 21287 Recruiting
University of Michigan Ann Arbor Michigan 48109 Recruiting
Henry Ford Cancer Institute Detroit Michigan 48202 Recruiting
Henry Ford Health Providence Southfield Hospital Southfield Michigan 48075 Recruiting
University Of Minnesota Minneapolis Minnesota 55455 Recruiting
Mayo Clinic Rochester Rochester Minnesota 55905 Recruiting
Regions Hospital Saint Paul Minnesota 55101 Completed
University of Nebraska Omaha Nebraska 68105 Recruiting
Dartmouth Hitchcock Medical Center Lebanon New Hampshire 03756 Recruiting
John Theurer Cancer Center at Hackensack University Medical Center Hackensack New Jersey 07601 Recruiting
Roswell Park Cancer Institute Buffalo New York 14263 Recruiting
Weill Cornell Medical College New York New York 10065 Recruiting
SUNY Upstate Medical University Syracuse New York 13210 Recruiting
Duke University Medical Center Durham North Carolina 27705 Recruiting
Gabrail Cancer Center Canton Ohio 44718 Recruiting
Louis Stokes Cleveland VA Med Ctr Cleveland Ohio 44106 Completed
Cleveland Clinic Cleveland Ohio 44195 Recruiting
Oregon Health And Science University Portland Oregon 97239 Completed
Penn State Milton S Hershey Medical Ctr Hershey Pennsylvania 17033 Recruiting
Thomas Jefferson University Philadelphia Pennsylvania 19107 4215 Recruiting
West Penn Hospital Pittsburgh Pennsylvania 15224 Recruiting
University Of Pittsburgh Medical Center UPMC Hillman Cancer Center Pittsburgh Pennsylvania 15232 Completed
Medical University of South Carolina Charleston South Carolina 29425-8900 Recruiting
Bon Secours Saint Francis Cancer Center Greenville South Carolina 29607 Recruiting
UT Southwestern Parkland Hospital Dallas Texas 75390 Recruiting
UT Southwestern Dallas Texas 75390 Recruiting
Houston Methodist Neal Cancer Center at Texas Medical Center Houston Texas 77030 Recruiting
Huntsman Cancer Institute Salt Lake City Utah 84112 Recruiting
University of Virginia Charlottesville Virginia 22903 Recruiting
Swedish Cancer Institute Seattle Washington 98104 Recruiting
Fred Hutchinson Cancer Research Center Seattle Washington 98109 Recruiting
NorthWest Medical Specialties, PLLC Tacoma Washington 98405 Recruiting
Gundersen Health System La Crosse Wisconsin 54601 Recruiting
Medical College Of Wisconsin Milwaukee Wisconsin 53226 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 193 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06208150, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 12, 2026 · Synced May 6, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06208150 live on ClinicalTrials.gov.

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