Vasopressin for Septic Shock Pragmatic Trial
Public ClinicalTrials.gov record NCT06217562. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Life-threatening low blood pressure due to a serious infection is called "septic shock." Septic shock is treated with vasopressors, medications that raise blood pressure. Sometimes first-line vasopressors are inadequate, prompting addition of a second-line vasopressor called vasopressin. However, the threshold at which to start vasopressin remains unclear. This pragmatic, cluster-randomized, cluster-crossover trial will evaluate two different strategies for septic shock treatment commonly used in current practice, comparing a lower versus a higher threshold for adding vasopressin to first-line vasopressors.
Study identification
- NCT ID
- NCT06217562
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 3,959 participants
Conditions and interventions
Conditions
Interventions
- Vasopressin Drug
- Recommendation to use a lower initiation threshold for vasopressin Other
- Recommendation to use a higher initiation threshold for vasopressin Other
Drug · Other
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 1, 2024 (Actual)
- Primary completion
- Feb 17, 2026 (Actual)
- Completion
- Jun 6, 2026 (Actual)
- Last update posted
- Aug 3, 2026
2024 – 2026
United States locations
- U.S. sites
- 13
- U.S. states
- 2
- U.S. cities
- 13
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Cassia Regional Hospital | Burley | Idaho | 83318 | — |
| American Fork Hospital | American Fork | Utah | 84003 | — |
| Cedar City Hospital | Cedar City | Utah | 84721 | — |
| Layton Hospital | Layton | Utah | 84041 | — |
| Logan Regional Hospital | Logan | Utah | 84341 | — |
| Intermountain Medical Center | Murray | Utah | 84107 | — |
| McKay-Dee Hospital | Ogden | Utah | 84403 | — |
| Park City Hospital | Park City | Utah | 84060 | — |
| Utah Valley Hospital | Provo | Utah | 84604 | — |
| Riverton Hospital | Riverton | Utah | 84065 | — |
| LDS Hospital | Salt Lake City | Utah | 84143 | — |
| Alta View Hospital | Sandy City | Utah | 84094 | — |
| St. George Regional Hospital | St. George | Utah | 84790 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06217562, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 3, 2026 · Synced Oct 17, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06217562 live on ClinicalTrials.gov.