A Trial to Evaluate the Safety and Efficacy of Benfotiamine in Patients With Early Alzheimer's Disease (BenfoTeam)
Public ClinicalTrials.gov record NCT06223360. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Seamless Phase 2A-Phase 2B Randomized Double-Blind Placebo- Controlled Trial to Evaluate the Safety and Efficacy of Benfotiamine in Patients With Early Alzheimer's Disease (BenfoTeam)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to learn more about the safety, effectiveness and tolerability of the study drug called Benfotiamine which may delay or slow the progression of the symptoms of early Alzheimer's disease.
Study identification
- NCT ID
- NCT06223360
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 406 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 50 Years to 89 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 27, 2024
- Primary completion
- Nov 30, 2027
- Completion
- Nov 30, 2027
- Last update posted
- Jun 3, 2026
2024 – 2027
United States locations
- U.S. sites
- 47
- U.S. states
- 20
- U.S. cities
- 38
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| St. Joseph's Hospital and Medical Center/Barrow Neurological Institute | Phoenix | Arizona | 85013 | — |
| Perseverance Research Center, LLC | Scottsdale | Arizona | 85253 | — |
| Banner Sun Health Research Institute | Sun City | Arizona | 85351 | — |
| The Neuron Clinic | Chula Vista | California | 91910 | — |
| University of California, Irvine | Irvine | California | 92697 | — |
| Pacific Research Network | Lemon Grove | California | 91945 | — |
| University of Southern California | Los Angeles | California | 90033 | — |
| Cedars Sinai, Los Angeles | Los Angeles | California | 90048 | — |
| Syrentis Clinical Research | Santa Ana | California | 92705 | — |
| JEM Research Institute | Atlantis | Florida | 33462 | — |
| Brain Matters Research | Delray Beach | Florida | 33445 | — |
| Neuropsychiatric Research Center of Southwest Florida | Fort Myers | Florida | 33912 | — |
| CCM Clinical Research Group, LLC | Miami | Florida | 33133 | — |
| Gonzalez MD & Aswad MD Health Services | Miami | Florida | 33135 | — |
| Miami Jewish Health | Miami | Florida | 33137 | — |
| Blue Medical Research Inc. | Miami | Florida | 33144 | — |
| Brainstorm Research | Miami | Florida | 33176 | — |
| Brain Matters Research (Kane Center) | Stuart | Florida | 34997 | — |
| Conquest Research | Winter Park | Florida | 32789 | — |
| Emory University Goizueta Alzheimer's Disease Research Center(GADRC) | Atlanta | Georgia | 30329 | — |
| Sandhill Research, LLC d/b/a Accel Research Sites | Decatur | Georgia | 30030 | — |
| Northwestern University Feinberg School of Medicine | Chicago | Illinois | 60611 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| Southern Illinois University | Springfield | Illinois | 62702 | — |
| University of Iowa | Iowa City | Iowa | 52242 | — |
| University of Kentucky | Lexington | Kentucky | 40504 | — |
| MedVadis Research | Waltham | Massachusetts | 02451 | — |
| University of Michigan, Ann Arbor | Ann Arbor | Michigan | 48109 | — |
| Rutgers, Robert Wood Johnson Medical School | New Brunswick | New Jersey | 08901 | — |
| Albany Medical College | Albany | New York | 12208 | — |
| Dent Neurologic Institute | Amherst | New York | 14226 | — |
| Integrative Clinical Trials | Brooklyn | New York | 11229 | — |
| Weill Cornell Medical College | New York | New York | 10021 | — |
| Mount Sinai School of Medicine | New York | New York | 10029 | — |
| Columbia University Irving Medical Center | New York | New York | 10032 | — |
| Nathan Kline Institute for Psychiatric Research | New York | New York | 10962 | — |
| SUNY Upstate Medical University | Syracuse | New York | 13210 | — |
| AMC Research LLC, dba Flourish Research | Matthews | North Carolina | 28105 | — |
| Case Western Reserve University | Cleveland | Ohio | 44106 | — |
| Ohio State University | Columbus | Ohio | 43221 | — |
| Oregon Health & Science University (OHSU) | Portland | Oregon | 97239 | — |
| Geisinger Memory and Cognition Center | Wilkes-Barre | Pennsylvania | 18711 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02903 | — |
| Ralph H. Johnson VA Health Care System | Charleston | South Carolina | 29401 | — |
| KCA Neurology | Tennessee City | Tennessee | 37067 | — |
| University of North Texas Health Science Center | Fort Worth | Texas | 76107 | — |
| Froedtert and Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06223360, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 3, 2026 · Synced Sep 6, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06223360 live on ClinicalTrials.gov.