A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease
Public ClinicalTrials.gov record NCT06226883. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of 3 Active Dose Regimens of MORF-057 in Adults With Moderately to Severely Active Crohn's Disease (GARNET)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a Phase 2, randomized, double-blind, placebo-controlled, multicenter study to evaluate the efficacy and safety of 3 active dose regimens of MORF-057 in adult study participants with moderately to severely active Crohn's disease (CD).
Study identification
- NCT ID
- NCT06226883
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company)
- Industry
- Enrollment
- 385 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 17, 2024
- Primary completion
- Aug 31, 2028
- Completion
- May 31, 2030
- Last update posted
- Sep 3, 2026
2024 – 2030
United States locations
- U.S. sites
- 25
- U.S. states
- 13
- U.S. cities
- 24
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Gastro Care Institute | Lancaster | California | 93534 | Recruiting |
| Infinity Clinical Research | San Diego | California | 92108 | Not yet recruiting |
| Peak Gastroenterology Associates - Colorado Springs | Colorado Springs | Colorado | 80921 | Recruiting |
| Clinical Research of Osceola | Kissimmee | Florida | 34741 | Recruiting |
| Bioresearch Partner-Kendale Lakes | Miami | Florida | 33155 | Recruiting |
| Endoscopic Research Inc | Orlando | Florida | 32803 | Recruiting |
| Tropical Clinical Trials | Palmetto Bay | Florida | 33176 | Recruiting |
| Atlanta Gastroenterology Specialists, PC | Atlanta | Georgia | 30024 | Recruiting |
| Atlanta Gastroenterology Associates (Part of United Digestive) | Atlanta | Georgia | 30342 | Recruiting |
| Tandem Clinical Research | Houma | Louisiana | 70360 | Recruiting |
| SSM Health DePaul Hospital- St. Louis | Bridgeton | Missouri | 063044 | Not yet recruiting |
| Las Vegas Clinical Trials | North Las Vegas | Nevada | 89030 | Not yet recruiting |
| Cross Creek Medical Clinic | Fayetteville | North Carolina | 28304 | Recruiting |
| Peters Medical Research | High Point | North Carolina | 27260 | Recruiting |
| Wake Research Associates | Raleigh | North Carolina | 27612 | Not yet recruiting |
| Palmetto Gastroenterology Clinical Research | Summerville | South Carolina | 29486 | Recruiting |
| Gastrointestinal Associates of Northeast Tennessee | Johnson City | Tennessee | 44060 | Recruiting |
| GI Alliance - Cedar Park | Cedar Park | Texas | 78613 | Recruiting |
| North Texas Gastroenterology | Denton | Texas | 76210 | Not yet recruiting |
| The University of Texas Health Science Center at Houston | Houston | Texas | 77030 | Recruiting |
| Prime Clinical Research - Lewisville | Lewisville | Texas | 75067 | Recruiting |
| Prime Clinical Research | Mansfield | Texas | 76063 | Recruiting |
| Tyler Research Institute, LLC | Tyler | Texas | 75701 | Recruiting |
| Care Access Research - Ogden | Ogden | Utah | 84403 | Recruiting |
| Gastroenterology Associates of Central Virginia | Lynchburg | Virginia | 24502 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 200 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06226883, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 3, 2026 · Synced Sep 11, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06226883 live on ClinicalTrials.gov.