Trial of Naltrexone/Bupropion for the Treatment of Methamphetamine Use Disorder
Public ClinicalTrials.gov record NCT06233799. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Randomized, Placebo-Controlled, Multi-Site Trial of Extended-Release Naltrexone Injection/Bupropion XL Tablets in the Treatment of Methamphetamine Use Disorder
Study identification
- NCT ID
- NCT06233799
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- National Institute on Drug Abuse (NIDA)
- NIH
- Enrollment
- 360 participants
Conditions and interventions
Conditions
Interventions
- extended release bupropion (BUP-XL) tablets (BUP-XL) Drug
- extended-release naltrexone (XR-NTX) Drug
- iPLB Drug
- oPLB Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 30, 2024
- Primary completion
- Oct 29, 2026
- Completion
- Apr 29, 2027
- Last update posted
- Feb 18, 2026
2024 – 2027
United States locations
- U.S. sites
- 11
- U.S. states
- 10
- U.S. cities
- 11
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205 | Recruiting |
| University of California Los Angeles | Los Angeles | California | 90038 | Recruiting |
| University of California at San Diego | San Diego | California | 92037 | Recruiting |
| Indiana University | Indianapolis | Indiana | 46202 | Recruiting |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | Recruiting |
| University of Minnesota | Minneapolis | Minnesota | 55415 | Recruiting |
| CODA | Portland | Oregon | 97214 | Recruiting |
| MUSC/BHS | Pickens | South Carolina | 29671 | Recruiting |
| University of Tennessee | Memphis | Tennessee | 38119 | Recruiting |
| University of Texas Southwestern Medical Center | Dallas | Texas | 75247 | Recruiting |
| University of Virginia | Charlottesville | Virginia | 22903 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06233799, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 18, 2026 · Synced May 5, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06233799 live on ClinicalTrials.gov.