Study to Evaluate Adverse Events, Optimal Dose, and Change in Disease Activity, With Livmoniplimab in Combination With Budigalimab Plus Chemotherapy Versus IV Infused Pembrolizumab Plus Chemotherapy in Adult Participants With Untreated Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
Public ClinicalTrials.gov record NCT06236438. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Phase 2/3 Study to Evaluate the Optimal Dose, Safety, and Efficacy of Livmoniplimab in Combination With Budigalimab Plus Chemotherapy Versus Pembrolizumab Plus Chemotherapy in Untreated Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
Study identification
- NCT ID
- NCT06236438
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Lead sponsor
- AbbVie
- Industry
- Enrollment
- 840 participants
Conditions and interventions
Conditions
Interventions
- Budigalimab Drug
- Carboplatin Drug
- Cisplatin Drug
- Livmoniplimab Drug
- Pembrolizumab Drug
- Pemetrexed Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 9, 2024
- Primary completion
- Sep 30, 2031
- Completion
- Sep 30, 2031
- Last update posted
- Feb 22, 2026
2024 – 2031
United States locations
- U.S. sites
- 19
- U.S. states
- 14
- U.S. cities
- 19
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Moores Cancer Center /ID# 267782 | La Jolla | California | 92037 | Recruiting |
| Memorial Hospital West /ID# 262221 | Pembroke Pines | Florida | 33028 | Recruiting |
| Bond Clinic /ID# 262611 | Winter Haven | Florida | 33880 | Recruiting |
| University Cancer & Blood Cent /ID# 261824 | Athens | Georgia | 30607 | Recruiting |
| The University of Chicago Medical Center /ID# 262259 | Chicago | Illinois | 60637-1443 | Recruiting |
| University of Kansas Medical Center /ID# 263196 | Westwood | Kansas | 66205 | Recruiting |
| Baptist Health Lexington /ID# 261823 | Lexington | Kentucky | 40503 | Recruiting |
| Cancer & Hematology Centers of Western Michigan - East /ID# 261826 | Grand Rapids | Michigan | 49546-7062 | Recruiting |
| Washington University-School of Medicine /ID# 262759 | St Louis | Missouri | 63110 | Recruiting |
| Stony Brook Cancer Center /ID# 261954 | Stony Brook | New York | 11794-0001 | Recruiting |
| Cone Health Cancer Center /ID# 262583 | Greensboro | North Carolina | 27403-1109 | Recruiting |
| Oncology Hematology Care, Inc - Blue Ash /ID# 262733 | Cincinnati | Ohio | 45252 | Recruiting |
| Guthrie Robert Packer Hospital /ID# 262758 | Sayre | Pennsylvania | 18840 | Recruiting |
| Renovatio clinical /ID# 262000 | El Paso | Texas | 79915-1803 | Completed |
| Houston Methodist Hospital /ID# 262722 | Houston | Texas | 77030 | Recruiting |
| Texas Oncology - Plano East /ID# 264356 | Plano | Texas | 75075 | Recruiting |
| Texas Oncology - San Antonio Medical Center - Research Drive /ID# 264311 | San Antonio | Texas | 78240 | Recruiting |
| Renovatio Clinical /ID# 261999 | The Woodlands | Texas | 77380-3181 | Completed |
| Vista Oncology - East Olympia /ID# 262303 | Olympia | Washington | 98506-5028 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 42 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06236438, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 22, 2026 · Synced May 8, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06236438 live on ClinicalTrials.gov.