A Trial to Investigate Teprotumumab Subcutaneous Administration Compared With Placebo in Male and Female Adult Participants With Moderate-to-severe Active Thyroid Eye Disease
Public ClinicalTrials.gov record NCT06248619. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-masked, Placebo-controlled, Parallel-group, Multicenter Trial to Evaluate the Efficacy, Safety and Tolerability of Subcutaneous Teprotumumab in Participants With Moderate-to-Severe Active Thyroid Eye Disease
Study identification
- NCT ID
- NCT06248619
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Amgen
- Industry
- Enrollment
- 89 participants
Conditions and interventions
Conditions
Interventions
- Placebo Other
- Teprotumumab Biological
Other · Biological
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 4, 2024
- Primary completion
- Jan 13, 2026
- Completion
- Sep 1, 2026
- Last update posted
- Jan 27, 2026
2024 – 2026
United States locations
- U.S. sites
- 11
- U.S. states
- 11
- U.S. cities
- 11
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Catalina Eye Care - NVISION - PPDS | Tucson | Arizona | 85712 | — |
| Advanced Quality Medical Research | Orland Park | Illinois | 60462 | — |
| W Kellogg Eye Center | Ann Arbor | Michigan | 48105-1912 | — |
| Las Vegas Endocrinology | Henderson | Nevada | 89074 | — |
| The Center for Eye and Facial Plastic Surgery | Somerset | New Jersey | 08773 | — |
| Casey Eye Institute -515 SW Campus Dr | Portland | Oregon | 97239-3130 | — |
| Scheie Eye Institute | Philadelphia | Pennsylvania | 19104-2640 | — |
| University of Tennessee Health Science Center - 848 Adams Ave | Memphis | Tennessee | 38103-3452 | — |
| Baylor College of Medicine-1977 Butler Blvd | Houston | Texas | 77030-4101 | — |
| University of Washington Eye Institute | Seattle | Washington | 98104-2433 | — |
| West Virginia University Eye Institute | Morgantown | West Virginia | 26506-1200 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 27 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06248619, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 27, 2026 · Synced May 17, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06248619 live on ClinicalTrials.gov.