SW-682 in Advanced Solid Tumors

ClinicalTrials.gov ID: NCT06251310

Public ClinicalTrials.gov record NCT06251310. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 5, 2026, 4:31 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1a/1b Dose Escalation, Dose Expansion Study of SW-682 in Participants With Advanced Solid Tumors Enriched for Those With Hippo Pathway Mutations

Study identification

NCT ID: NCT06251310
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 1
Lead sponsor: SpringWorks Therapeutics, Inc.; Industry
Enrollment: 186 participants

Conditions and interventions

Conditions

Interventions

Combination Therapy Drug
SW-682 Drug

Drug

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Jul 29, 2024
Primary completion: Dec 31, 2029
Completion: May 31, 2030
Last update posted: Mar 31, 2026

2024 – 2030

United States locations

U.S. sites: 8
U.S. states: 5
U.S. cities: 7

Facility	City	State	ZIP	Site status
SpringWorks Clinical Trial Site	Scottsdale	Arizona	85258	Recruiting
UC San Diego Moores Cancer Center	La Jolla	California	92093	Recruiting
USC/Norris Comprehensive Cancer Center	Los Angeles	California	90033	Recruiting
SpringWorks Clinical Trial Site	Los Angeles	California	90095	Recruiting
University Hospitals Cleveland Medical Center	Cleveland	Ohio	44106	Recruiting
Knight Cancer Institute Clinical Trials	Portland	Oregon	97239	Recruiting
Mary Crowley Cancer Research	Dallas	Texas	75230	Recruiting
The University of Texas MD Anderson Cancer Center	Houston	Texas	77030	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT06251310, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Mar 31, 2026 · Synced May 5, 2026

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The complete protocol, eligibility criteria, and contact information for NCT06251310 live on ClinicalTrials.gov.

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