Study to Evaluate the Efficacy, Safety, and Tolerability of an Anti-MTBR Tau Monoclonal Antibody (BMS-986446) in Participants With Early Alzheimer's Disease
Public ClinicalTrials.gov record NCT06268886. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Placebo-controlled, Global Proof-of-concept Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986446, an Anti-MTBR Tau Monoclonal Antibody, in Participants With Early Alzheimer's Disease (TargetTau-1)
Study identification
- NCT ID
- NCT06268886
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Bristol-Myers Squibb
- Industry
- Enrollment
- 310 participants
Conditions and interventions
Conditions
Not listed
Interventions
Not listed
Eligibility (public fields only)
- Age range
- 50 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 19, 2024
- Primary completion
- Mar 17, 2027
- Completion
- Mar 17, 2027
- Last update posted
- Jul 23, 2025
2024 – 2027
United States locations
- U.S. sites
- 14
- U.S. states
- 2
- U.S. cities
- 12
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Local Institution - 0068 | Chandler | Arizona | 85226-3732 | — |
| Local Institution - 0102 | Gilbert | Arizona | 85297-0441 | — |
| Local Institution - 0019 | Phoenix | Arizona | 85004 | — |
| Local Institution - 0018 | Scottsdale | Arizona | 85253 | — |
| Local Institution - 0026 | Scottsdale | Arizona | 85258-4595 | — |
| Local Institution - 0077 | Tucson | Arizona | 85718-6522 | — |
| Local Institution - 0038 | Tucson | Arizona | 85718-6632 | — |
| Local Institution - 0164 | Encino | California | 91316-1511 | — |
| Local Institution - 0139 | Fullerton | California | 92835-1040 | — |
| Local Institution - 0191 | Irvine | California | 92614-9403 | — |
| Local Institution - 0234 | Long Beach | California | 90804-2128 | — |
| Local Institution - 0142 | Los Alamitos | California | 90720-3589 | — |
| Local Institution - 0037 | Napa | California | 94558-2415 | — |
| Local Institution - 0209 | Sacramento | California | 95816 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06268886, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 23, 2025 · Synced May 18, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06268886 live on ClinicalTrials.gov.