A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer Compared With Sham Treatment in Participants With Diabetic Retinopathy (DR)
Public ClinicalTrials.gov record NCT06270836. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Prospective, Randomized, Double-masked, Sham-controlled, Multi-center, Two-arm, Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal Tarcocimab Tedromer in Participants With Diabetic Retinopathy (DR) - GLOW2
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will demonstrate that tarcocimab 5 mg is superior to sham treatment in participants with DR.
Study identification
- NCT ID
- NCT06270836
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 255 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 1, 2024 (Actual)
- Primary completion
- Feb 13, 2026 (Actual)
- Completion
- Feb 13, 2026 (Actual)
- Last update posted
- May 13, 2026
2024 – 2026
United States locations
- U.S. sites
- 38
- U.S. states
- 18
- U.S. cities
- 37
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Retina Associates SW | Tucson | Arizona | 85704 | — |
| Retina Consultants of Orange County | Fullerton | California | 92835 | — |
| Global Research Management, Inc. - Lugene Eye Institute | Glendale | California | 91204 | — |
| Retinal Consultants Medical Group, Inc. | Modesto | California | 95356 | — |
| Retina Consultants of Southern California | Redlands | California | 92374 | — |
| Retinal Consultants Medical Group, Inc. | Sacramento | California | 95825 | — |
| Retina Group of New England, PC | Waterford | Connecticut | 06385 | — |
| Retina Group of Florida | Fort Lauderdale | Florida | 33308 | — |
| Florida Eye Associates | Melbourne | Florida | 32901 | — |
| Center for Retina and Macular Disease | Winter Haven | Florida | 33880 | — |
| Southeast Retina Center | Augusta | Georgia | 30909 | — |
| Springfield Clinic LLP | Springfield | Illinois | 62703 | — |
| Associated Vitreoretinal and Uveitis Consultants | Carmel | Indiana | 46290 | — |
| Cumberland Valley Retina Consultants | Hagerstown | Maryland | 21740 | — |
| Retina Consultants of Nevada | Henderson | Nevada | 89052 | — |
| Envision Ocular, LLC | Bloomfield | New Jersey | 07003 | — |
| Asheville Eye Associates | Asheville | North Carolina | 28803 | — |
| North Carolina Retina Associates (Cary) | Cary | North Carolina | 27511 | — |
| North Carolina Retina Associates (Wake Forest) | Wake Forest | North Carolina | 27587 | — |
| Cascade Medical Research Institute | Springfield | Oregon | 97477 | — |
| Erie Retina Research | Erie | Pennsylvania | 16507 | — |
| Charleston Neuroscience Institute | Charleston | South Carolina | 29414 | — |
| Charles Retina Institute | Germantown | Tennessee | 38138 | — |
| Southeastern Retina Associates PC | Knoxville | Tennessee | 37922 | — |
| Retina Research Institute of Texas | Abilene | Texas | 79606 | — |
| Panhandle Eye Group, LLP. - Southwest Retina Specialists | Amarillo | Texas | 79106 | — |
| Austin Retina Associates, PLLC (Austin) | Austin | Texas | 78705-1169 | — |
| Austin Research Center for Retina | Austin | Texas | 78705 | — |
| Retina Consultants of Texas (Bellaire) | Bellaire | Texas | 77401 | — |
| Star Vision Research | Burleson | Texas | 76028 | — |
| Retina Consultants of Texas (Katy) | Katy | Texas | 77494 | — |
| Texas Retina Associates | Plano | Texas | 75075 | — |
| Austin Retina Associates, PLLC (Round Rock) | Round Rock | Texas | 78681 | — |
| Retina Consultants of Texas (San Antonio) | San Antonio | Texas | 78240 | — |
| Retina Consultants of Texas (Woodlands) | The Woodlands | Texas | 77384 | — |
| Piedmont Eye Center | Lynchburg | Virginia | 24502 | — |
| Pacific Northwest Retina (Bellevue) | Bellevue | Washington | 98004 | — |
| Spokane Eye Clinical Research | Spokane | Washington | 99204 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06270836, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 13, 2026 · Synced Oct 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06270836 live on ClinicalTrials.gov.