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Active, not recruiting No phase listed Observational Accepts healthy volunteers

Biomarkers for Vascular Contributions to Cognitive Impairment and Dementia Consortium

ClinicalTrials.gov ID: NCT06284213

Public ClinicalTrials.gov record NCT06284213. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 1, 2026, 3:58 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Biomarkers for Vascular Contributions to Cognitive Impairment and Dementia (MarkVCID) is an NIH-funded consortium dedicated to finding biomarkers involved in age-related thinking and memory problems. Alzheimer's disease and other dementias leave signatures on brain scans or in the blood called biomarkers. The MarkVCID study will measure a panel of candidate biomarkers in 1800 participants and watch them closely to see what they tell us about changes in brain function and risk of memory loss. Age-related problems in thinking and memory represent some of the greatest risks to public health in the US and globally. Diseases that affect small blood vessels in the brain have been shown to be major contributors to these changes. However, research and patient care can be held back by limited biomarkers that identify who should be treated. The MarkVCID Consortium includes 17 US medical centers, a Coordinating Center, an External Advisory Committee, and NIH leadership. Data and biospecimens collected as part of this research study will be stored in a research database and biorepositories, so that researchers can use this information to study brain function.

Study identification

NCT ID
NCT06284213
Recruitment status
Active, not recruiting
Study type
Observational
Phase
Not listed
Enrollment
1,892 participants

Conditions and interventions

Interventions

Other

Eligibility (public fields only)

Age range
60 Years to 90 Years
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 28, 2021
Primary completion
Jun 30, 2027
Completion
Jun 30, 2027
Last update posted
Jan 28, 2025

2021 – 2027

United States locations

U.S. sites
17
U.S. states
10
U.S. cities
15
Facility City State ZIP Site status
University of Southern California Los Angeles California 90033
University of California Los Angeles Los Angeles California 90095
University of California Davis Sacramento California 95817
University of California San Francisco San Francisco California 94158
Olive View - UCLA Medical Center Sylmar California 91342
Mayo Clinic Florida Jacksonville Florida 32224
Rush University Medical Center & Illinois Institute of Technology Chicago Illinois 60612
University of Kentucky Lexington Kentucky 40536
University of Maryland, Baltimore Baltimore Maryland 21201
Johns Hopkins University Baltimore Maryland 21287
Mayo Clinic Rochester Rochester Minnesota 55901
University of Mississippi Medical Center Jackson Mississippi 39216
Washington University in St. Louis St Louis Missouri 63110
University of New Mexico Albuquerque New Mexico 87131
University of Texas Southwestern Dallas Texas 75390
University of Texas Health Science Center Houston Houston Texas 77030
University of Texas Health Science Center San Antonio San Antonio Texas 78229

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06284213, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 28, 2025 · Synced Sep 1, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06284213 live on ClinicalTrials.gov.

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