Study of GS-1427 in Participants With Moderately to Severely Active Ulcerative Colitis
Public ClinicalTrials.gov record NCT06290934. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Multicenter, Dose-Ranging Study Evaluating the Efficacy and Safety of GS-1427 in Adult Participants With Moderately to Severely Active Ulcerative Colitis (UC)
Study identification
- NCT ID
- NCT06290934
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Gilead Sciences
- Industry
- Enrollment
- 228 participants
Conditions and interventions
Conditions
Interventions
- Placebo-to-match emvistegrast Drug
- emvistegrast Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Not listed
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 26, 2024
- Primary completion
- Mar 3, 2026
- Completion
- Mar 31, 2028
- Last update posted
- Apr 8, 2026
2024 – 2028
United States locations
- U.S. sites
- 57
- U.S. states
- 21
- U.S. cities
- 49
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Onyx Clinical Research (Clinic Location) | Peoria | Arizona | 85381 | — |
| Om Research LLC | Camarillo | California | 93010 | — |
| VVCRD Research | Garden Grove | California | 92845 | — |
| 310 Clinical Research | Inglewood | California | 90301 | — |
| US San Diego Health System | La Jolla | California | 92037 | — |
| Om Research LLC | Lancaster | California | 93534 | — |
| UCSF Benioff Children's Hospital Oakland | Oakland | California | 94609 | — |
| University Of California, Davis | Sacramento | California | 95817 | — |
| SDG Clinical Research, LLC | San Diego | California | 92103 | — |
| Acclaim Clinical Research | San Diego | California | 92120 | — |
| Peak Gastroenterology Associates | Colorado Springs | Colorado | 80907 | — |
| Peak Gastroenterology Associates | Colorado Springs | Colorado | 80921 | — |
| Gastro Florida | Clearwater | Florida | 33756 | — |
| Best Quality Research, Inc | Hialeah | Florida | 33016 | — |
| United Research Institute LLC | Hialeah | Florida | 33016 | — |
| University of Miami Hospital and Clinics, Sylvester Comprehensive Cancer Center(Drug shipment)-Research Pharmacy | Miami | Florida | 33136 | — |
| Medical Professional Clinical Research Center, Inc. | Miami | Florida | 33155 | — |
| Blessed Health Care & Research, Inc | Miami | Florida | 33173 | — |
| Alliance Clinical Research of Tampa, LLC | New Port Richey | Florida | 34653 | — |
| Digestive and Liver Center of Florida, LLC | Orlando | Florida | 32825 | — |
| Clinical Research of Osceola | Orlando | Florida | 34741 | — |
| Encore Medical Research of Weston, LLC | Weston | Florida | 33331 | — |
| EBGS Clinical Research Center | Snellville | Georgia | 30078 | — |
| The University of Chicago Medical Center (Duchossois Center for Advanced Medicine) | Chicago | Illinois | 60637 | — |
| Onyx Clinical Research | Peoria | Illinois | 85381 | — |
| Robley Rex VA Medical Center | Louisville | Kentucky | 40206 | — |
| Louisiana Research Center, LLC | Shreveport | Louisiana | 71105 | — |
| Johns Hopkins Bayview Medical Center | Baltimore | Maryland | 21224 | — |
| Gastroenterology Associates of Western Michigan, PLC d.b.a. West Michigan Clinical Research Center. | Wyoming | Michigan | 49519 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Gastroenterology Associates of North Mississippi | Oxford | Mississippi | 38655 | — |
| Digestive Health Specialists (Clinic Visits) | Tupelo | Mississippi | 38801 | — |
| St Charles Clinical Research | Weldon Spring | Missouri | 63304 | — |
| Tandem - Allied Clinical Research, LLC | Freehold | New Jersey | 07728 | — |
| N.Y. Total Medical Care, PC | Brooklyn | New York | 11215 | — |
| NYU Langone Long Island Clinical Research Associates | Great Neck | New York | 11021 | — |
| Lenox Hill Hospital | Manhasset | New York | 11030 | — |
| NYU Grossman School of Medicne | New York | New York | 10016 | — |
| Carolina Research | Greenville | North Carolina | 27834 | — |
| Piedmont Healthcare | Statesville | North Carolina | 28625 | — |
| Dayton Gastroenterology, LLC | Beavercreek | Ohio | 45440 | — |
| Gastro Health Research | Cincinnati | Ohio | 45219 | — |
| NexGen Research | Lima | Ohio | 45801 | — |
| Gastro Intestinal Research Institute of Northern Ohio, LLC | Westlake | Ohio | 44145 | — |
| Penn State University Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033 | — |
| Skyline gastroenterology of west Tennessee | Jackson | Tennessee | 38301 | — |
| Quality Medical Research | Nashville | Tennessee | 37211 | — |
| Vanderbilt Inflammatory Bowel Disease Clinic | Nashville | Tennessee | 37232 | — |
| Gastroenterology Research of San Antonio | Fredericksburg | Texas | 78624 | — |
| Amel Med Llc | Georgetown | Texas | 78628 | — |
| GI Alliance - Mansfield | Mansfield | Texas | 76063 | — |
| Clinical Associates in Research Therapeutics of America, LLC | San Antonio | Texas | 78212 | — |
| Southern Star Research Institute, LLC. | San Antonio | Texas | 78229 | — |
| Tyler Research Institute, LLC. | Tyler | Texas | 75701 | — |
| University of Virginia Medical Center | Charlottesville | Virginia | 22908 | — |
| Emeritas Research Group | Lansdowne Town Center | Virginia | 20176 | — |
| Gastroenterology Consultants of Southwest Virginia | Roanoke | Virginia | 24014 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 124 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06290934, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 8, 2026 · Synced Apr 22, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06290934 live on ClinicalTrials.gov.