ClinicalTrials.gov record
Active, not recruiting Phase 2 Interventional

Study of GS-1427 in Participants With Moderately to Severely Active Ulcerative Colitis

ClinicalTrials.gov ID: NCT06290934

Public ClinicalTrials.gov record NCT06290934. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Apr 22, 2026, 8:33 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Multicenter, Dose-Ranging Study Evaluating the Efficacy and Safety of GS-1427 in Adult Participants With Moderately to Severely Active Ulcerative Colitis (UC)

Study identification

NCT ID
NCT06290934
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 2
Lead sponsor
Gilead Sciences
Industry
Enrollment
228 participants

Conditions and interventions

Interventions

  • Placebo-to-match emvistegrast Drug
  • emvistegrast Drug

Drug

Eligibility (public fields only)

Age range
18 Years to 75 Years
Sex
All
Healthy volunteers
Not listed

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 26, 2024
Primary completion
Mar 3, 2026
Completion
Mar 31, 2028
Last update posted
Apr 8, 2026

2024 – 2028

United States locations

U.S. sites
57
U.S. states
21
U.S. cities
49
Facility City State ZIP Site status
Onyx Clinical Research (Clinic Location) Peoria Arizona 85381
Om Research LLC Camarillo California 93010
VVCRD Research Garden Grove California 92845
310 Clinical Research Inglewood California 90301
US San Diego Health System La Jolla California 92037
Om Research LLC Lancaster California 93534
UCSF Benioff Children's Hospital Oakland Oakland California 94609
University Of California, Davis Sacramento California 95817
SDG Clinical Research, LLC San Diego California 92103
Acclaim Clinical Research San Diego California 92120
Peak Gastroenterology Associates Colorado Springs Colorado 80907
Peak Gastroenterology Associates Colorado Springs Colorado 80921
Gastro Florida Clearwater Florida 33756
Best Quality Research, Inc Hialeah Florida 33016
United Research Institute LLC Hialeah Florida 33016
University of Miami Hospital and Clinics, Sylvester Comprehensive Cancer Center(Drug shipment)-Research Pharmacy Miami Florida 33136
Medical Professional Clinical Research Center, Inc. Miami Florida 33155
Blessed Health Care & Research, Inc Miami Florida 33173
Alliance Clinical Research of Tampa, LLC New Port Richey Florida 34653
Digestive and Liver Center of Florida, LLC Orlando Florida 32825
Clinical Research of Osceola Orlando Florida 34741
Encore Medical Research of Weston, LLC Weston Florida 33331
EBGS Clinical Research Center Snellville Georgia 30078
The University of Chicago Medical Center (Duchossois Center for Advanced Medicine) Chicago Illinois 60637
Onyx Clinical Research Peoria Illinois 85381
Robley Rex VA Medical Center Louisville Kentucky 40206
Louisiana Research Center, LLC Shreveport Louisiana 71105
Johns Hopkins Bayview Medical Center Baltimore Maryland 21224
Gastroenterology Associates of Western Michigan, PLC d.b.a. West Michigan Clinical Research Center. Wyoming Michigan 49519
Mayo Clinic Rochester Minnesota 55905
Gastroenterology Associates of North Mississippi Oxford Mississippi 38655
Digestive Health Specialists (Clinic Visits) Tupelo Mississippi 38801
St Charles Clinical Research Weldon Spring Missouri 63304
Tandem - Allied Clinical Research, LLC Freehold New Jersey 07728
N.Y. Total Medical Care, PC Brooklyn New York 11215
NYU Langone Long Island Clinical Research Associates Great Neck New York 11021
Lenox Hill Hospital Manhasset New York 11030
NYU Grossman School of Medicne New York New York 10016
Carolina Research Greenville North Carolina 27834
Piedmont Healthcare Statesville North Carolina 28625
Dayton Gastroenterology, LLC Beavercreek Ohio 45440
Gastro Health Research Cincinnati Ohio 45219
NexGen Research Lima Ohio 45801
Gastro Intestinal Research Institute of Northern Ohio, LLC Westlake Ohio 44145
Penn State University Milton S. Hershey Medical Center Hershey Pennsylvania 17033
Skyline gastroenterology of west Tennessee Jackson Tennessee 38301
Quality Medical Research Nashville Tennessee 37211
Vanderbilt Inflammatory Bowel Disease Clinic Nashville Tennessee 37232
Gastroenterology Research of San Antonio Fredericksburg Texas 78624
Amel Med Llc Georgetown Texas 78628
GI Alliance - Mansfield Mansfield Texas 76063
Clinical Associates in Research Therapeutics of America, LLC San Antonio Texas 78212
Southern Star Research Institute, LLC. San Antonio Texas 78229
Tyler Research Institute, LLC. Tyler Texas 75701
University of Virginia Medical Center Charlottesville Virginia 22908
Emeritas Research Group Lansdowne Town Center Virginia 20176
Gastroenterology Consultants of Southwest Virginia Roanoke Virginia 24014

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 124 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06290934, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 8, 2026 · Synced Apr 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06290934 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →