A First-In-Human Study of LY3954068 in Participants With Early Symptomatic Alzheimer's Disease
Public ClinicalTrials.gov record NCT06297590. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Single- and Multiple-Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of LY3954068 in Patients With Early Symptomatic Alzheimer's Disease
Study identification
- NCT ID
- NCT06297590
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- Eli Lilly and Company
- Industry
- Enrollment
- 48 participants
Conditions and interventions
Conditions
Interventions
- Flortaucipir F18 Drug
- LY3954068 Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 50 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 14, 2024
- Primary completion
- Jan 31, 2027
- Completion
- Jan 31, 2027
- Last update posted
- Apr 19, 2026
2024 – 2027
United States locations
- U.S. sites
- 6
- U.S. states
- 5
- U.S. cities
- 6
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| K2 Medical Research, LLC | Maitland | Florida | 32751 | Recruiting |
| Charter Research, LLC | The Villages | Florida | 32162 | Recruiting |
| CenExel iResearch, LLC (CenExel iRA) | Decatur | Georgia | 30030 | Recruiting |
| Massachusetts General Hospital (MGH) | Charlestown | Massachusetts | 02129 | Not yet recruiting |
| CenExel AMRI | Toms River | New Jersey | 08755 | Recruiting |
| Duke University | Durham | North Carolina | 27710 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 4 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06297590, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 19, 2026 · Synced May 6, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06297590 live on ClinicalTrials.gov.