ClinicalTrials.gov record
A Study to Test if Trevogrumab or Trevogrumab With Garetosmab When Taken With Semaglutide is Safe and How Well They Work in Adult Patients With Obesity for Weight Loss, Fat Loss, and Lean Mass Preservation
ClinicalTrials.gov ID: NCT06299098
Public ClinicalTrials.gov record NCT06299098. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 10, 2026, 8:53 AM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind Study of The Efficacy and Safety of Trevogrumab, With or Without Garetosmab, in Addition to Semaglutide in Patients With Obesity
Study identification
- NCT ID
- NCT06299098
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Regeneron Pharmaceuticals
- Industry
- Enrollment
- 1,005 participants
Conditions and interventions
Conditions
Interventions
- Garetosmab Drug
- Matching Placebo-Garetosmab Drug
- Matching Placebo-Part A Drug
- Matching Placebo-Trevogrumab Drug
- Semaglutide Drug
- Trevogrumab-Part A Drug
- Trevogrumab-Part B and Part C Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 12, 2024
- Primary completion
- May 17, 2026
- Completion
- Oct 29, 2026
- Last update posted
- May 7, 2026
2024 – 2026
United States locations
- U.S. sites
- 58
- U.S. states
- 25
- U.S. cities
- 54
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Pinnacle Research Group | Anniston | Alabama | 36207 | — |
| Cullman Clinical Trials | Cullman | Alabama | 35055 | — |
| Foothills Research Center Cct Research | Phoenix | Arizona | 85044 | — |
| Anaheim Clinical Trials | Anaheim | California | 92801 | — |
| ProSciento | Chula Vista | California | 91911 | — |
| Valiance Clinical Research- Huntington Park | Huntington Park | California | 91356 | — |
| Velocity, San Diego | La Mesa | California | 91941 | — |
| Northern California Research | Sacramento | California | 95821 | — |
| Acclaim Clinical Research | San Diego | California | 92120 | — |
| Metabolic Institute of America | Tarzana | California | 91356 | — |
| Valiance Clinical Research | Tarzana | California | 91356 | — |
| Southwest General Healthcare Center | Fort Myers | Florida | 33907 | — |
| Westside Center for Clinical Research | Jacksonville | Florida | 32205 | — |
| Jacksonville Center for Clinical Research | Jacksonville | Florida | 32216 | — |
| IMA Clinical Research St. Petersburg | St. Petersburg | Florida | 33709 | — |
| Precision Clinical Research, LLC | Sunrise | Florida | 33351 | — |
| Clinical Research of West Florida, Inc. | Tampa | Florida | 33606 | — |
| Clinical Research of Central Florida - Bond Clinic | Winter Haven | Florida | 33880 | — |
| Center for Advanced Research and Education | Gainesville | Georgia | 30501 | — |
| Balanced Life Health Care Solutions | Lawrenceville | Georgia | 30046 | — |
| North Georgia Clinical Research | Woodstock | Georgia | 30189 | — |
| East-West Medical Research Institute | Honolulu | Hawaii | 96814 | — |
| Elite Clinical Trials LLLP | Blackfoot | Idaho | 83221 | — |
| Prairie Education and Research Cooperative (PERC) | Springfield | Illinois | 62701 | — |
| The South Bend Clinic Center for Research | South Bend | Indiana | 46617 | — |
| Cotton O'Neil Clinical Research Center | Topeka | Kansas | 66606 | — |
| L-MARC Research Center | Louisville | Kentucky | 40213 | — |
| Tandem Clinical Research GI, LLC | Marrero | Louisiana | 70072 | — |
| IMA Clinical Research Monroe - Armand | Monroe | Louisiana | 71201 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Prime Health and Wellness Clinic | Fayette | Mississippi | 39069 | — |
| Olive Branch Family Medical Center | Olive Branch | Mississippi | 38654 | — |
| Sky Integrative Medical Center Skycrng | Ridgeland | Mississippi | 39157 | — |
| Jefferson City Medical Group | Jefferson City | Missouri | 65109 | — |
| Clinvest Research | Springfield | Missouri | 65807 | — |
| Mercury Street Medical Group, PLLC | Butte | Montana | 59701 | — |
| Hassman Research Institute | Berlin | New Jersey | 08009 | — |
| Accellacare Clinical Research, Raleigh Medical Group | Raleigh | North Carolina | 27609 | — |
| Accellacare of Salisbury | Salisbury | North Carolina | 28144 | — |
| Accellacare of Piedmont, Piedmont Healthcare | Statesville | North Carolina | 28625 | — |
| Pmg Research of Wilmington Llc | Wilmington | North Carolina | 28401 | — |
| PMG Research of Winston-Salem, LLC | Winston-Salem | North Carolina | 27103 | — |
| Javara Incorporated at Wake Forest University Health Sciences | Winston-Salem | North Carolina | 27157 | — |
| Velocity Clinical Research Inc. | Cincinnati | Ohio | 45219 | — |
| AMR Norman | Norman | Oklahoma | 73069 | — |
| Altoona Center for Clinical Research | Duncansville | Pennsylvania | 16635 | — |
| Tribe Clinical Research Llc | Greenville | South Carolina | 29607 | — |
| PMG Research of Charleston | Mt. Pleasant | South Carolina | 29464 | — |
| Pmg Research of Bristol | Bristol | Tennessee | 37620 | — |
| Chattanooga Medical Research | Chattanooga | Tennessee | 37412 | — |
| PMG Research of Knoxville - Merchant Drive | Knoxville | Tennessee | 37912 | — |
| PMG Research of Knoxville - Emory Road | Knoxville | Tennessee | 37938 | — |
| Velocity Clinical Research Dallas | Dallas | Texas | 75230 | — |
| Medresearch Inc | El Paso | Texas | 79902 | — |
| Valley Institute of Research | Fort Worth | Texas | 76164 | — |
| Consano Clinical Research | Shavano Park | Texas | 78231 | — |
| Charlottesville Medical Research | Charlottesville | Virginia | 22911 | — |
| Health Research of Hampton Roads, Inc. | Newport News | Virginia | 23606 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06299098, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 7, 2026 · Synced May 10, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06299098 live on ClinicalTrials.gov.