Study to Evaluate Avacopan in Combination With a Rituximab or Cyclophosphamide-containing Regimen, in Children From 6 Years to < 18 Years of Age With AAV.

ClinicalTrials.gov ID: NCT06321601

Public ClinicalTrials.gov record NCT06321601. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 6, 2026, 8:50 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3, Open-label, Uncontrolled Single-arm Study to Evaluate the Efficacy, Pharmacokinetics, and Safety of Avacopan in Combination With a Rituximab or a Cyclophosphamide-containing Regimen in Children From 6 Years to < 18 Years of Age With Active ANCA-associated Vasculitis (AAV)

Study identification

NCT ID: NCT06321601
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 3
Lead sponsor: Amgen; Industry
Enrollment: 20 participants

Conditions and interventions

Conditions

Vasculitis

Interventions

Avacopan Drug

Drug

Eligibility (public fields only)

Age range: 6 Years to 17 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Oct 21, 2024
Primary completion: Sep 25, 2028
Completion: Sep 25, 2028
Last update posted: Apr 30, 2026

2024 – 2028

United States locations

U.S. sites: 10
U.S. states: 8
U.S. cities: 10

Facility	City	State	ZIP	Site status
Emory University	Atlanta	Georgia	30322	Recruiting
Riley Hospital for Children	Indianapolis	Indiana	46202	Recruiting
University of Minnesota Masonic Childrens Hospital Discovery Clinic	Minneapolis	Minnesota	55454	Recruiting
Cohen Children Medical Center	Lake Success	New York	11042	Recruiting
University of North Carolina	Chapel Hill	North Carolina	27599	Recruiting
Wake Forest University Health Sciences	Charlotte	North Carolina	28203	Recruiting
Akron Childrens Hospital	Akron	Ohio	44308	Recruiting
Cleveland Clinic Foundation	Cleveland	Ohio	44195	Recruiting
University of Pittsburgh Medical Center Childrens Hospital of Pittsburgh	Pittsburgh	Pennsylvania	15224	Recruiting
Texas Childrens Hospital	Houston	Texas	77030	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 21 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT06321601, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Apr 30, 2026 · Synced May 6, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06321601 live on ClinicalTrials.gov.

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