Crohn's Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects With Moderately to Severely Active Crohn's Disease

ClinicalTrials.gov ID: NCT06332534

Public ClinicalTrials.gov record NCT06332534. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Apr 29, 2026, 9:04 AM EDT

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Official title

A Phase 3 Multicenter Study to Evaluate Efficacy, Safety, and Pharmacokinetics of Upadacitinib With Open-Label Induction, Randomized, Double-Blind Maintenance and Open-Label Long-Term Extension in Pediatric Subjects With Moderately to Severely Active Crohn's Disease and Inadequate Response, Intolerance, or Medical Contraindications to Corticosteroids, Immunosuppressants, and/or Biologic Therapy

Study identification

NCT ID: NCT06332534
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 3
Lead sponsor: AbbVie; Industry
Enrollment: 110 participants

Conditions and interventions

Conditions

Crohn's Disease

Interventions

Upadacitinib Drug

Drug

Eligibility (public fields only)

Age range: 2 Years to 17 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Aug 7, 2024
Primary completion: May 31, 2027
Completion: Nov 30, 2034
Last update posted: Apr 14, 2026

2024 – 2034

United States locations

U.S. sites: 12
U.S. states: 11
U.S. cities: 12

Facility	City	State	ZIP	Site status
UCSF Benioff Children's Hospital - Oakland /ID# 262217	Oakland	California	94609	Recruiting
Lucile Packard Children's Hospital /ID# 262193	Palo Alto	California	94304	Recruiting
Children's Hospital Colorado - Aurora /ID# 262207	Aurora	Colorado	80045	Recruiting
Connecticut Children's Medical Center - Hartford /ID# 262256	Hartford	Connecticut	06106	Recruiting
OSF St. Francis Medical Center /ID# 262192	Peoria	Illinois	61637-0001	Recruiting
Indiana University Health Riley Hospital for Children /ID# 262215	Indianapolis	Indiana	46202	Recruiting
Boston Children's Hospital /ID# 262191	Boston	Massachusetts	02115	Recruiting
MNGI Digestive Health, P. A. /ID# 262204	Minneapolis	Minnesota	55413-2195	Recruiting
Icahn School of Medicine at Mount Sinai /ID# 262216	New York	New York	10029	Recruiting
Univ NC Chapel Hill /ID# 262198	Chapel Hill	North Carolina	27514-4220	Recruiting
UH Cleveland Medical Center /ID# 262188	Cleveland	Ohio	44106	Recruiting
Children's Hospital of Philadelphia - Main /ID# 262197	Philadelphia	Pennsylvania	19104-4319	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 71 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT06332534, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Apr 14, 2026 · Synced Apr 29, 2026

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The complete protocol, eligibility criteria, and contact information for NCT06332534 live on ClinicalTrials.gov.

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