A Study to Evaluate Efficacy and Safety of Intravenous Sabirnetug in Participants With Early Alzheimer's Disease (ALTITUDE-AD)
Public ClinicalTrials.gov record NCT06335173. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2 Double-Blind, Randomized, Placebo-Controlled Trial to Evaluate the Efficacy and Safety of Intravenous Sabirnetug in Early Alzheimer's Disease
Study identification
- NCT ID
- NCT06335173
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Acumen Pharmaceuticals
- Industry
- Enrollment
- 542 participants
Conditions and interventions
Conditions
Interventions
- Placebo Drug
- sabirnetug Drug
Drug
Eligibility (public fields only)
- Age range
- 50 Years to 90 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 28, 2024
- Primary completion
- Sep 30, 2026
- Completion
- Sep 30, 2026
- Last update posted
- Oct 26, 2025
2024 – 2026
United States locations
- U.S. sites
- 44
- U.S. states
- 18
- U.S. cities
- 43
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| The Neurology Center of Southern California - Carlsbad | Carlsbad | California | 92011-4219 | — |
| Neurology Center of North Orange County | Fullerton | California | 92835 | — |
| Irvine Medical Research | Irvine | California | 92614 | — |
| Healthy Brain Research | Long Beach | California | 90804 | — |
| Syrentis Clinical Research | Santa Ana | California | 92705 | — |
| CenExel - California Neuroscience Research Medical Group, Inc (CNR) | Sherman Oaks | California | 91403-2131 | — |
| Research Center for Clinical Studies, LLC | Norwalk | Connecticut | 06851-4903 | — |
| Re:Cognition Health - Fairfax | Washington D.C. | District of Columbia | 22031 | — |
| JEM Research Institute | Atlantis | Florida | 33462 | — |
| Bradenton Research Center | Bradenton | Florida | 34205 | — |
| Gil Fernandez-Yera, MD, PA | Coral Gables | Florida | 33135 | — |
| Brain Matters Research | Delray Beach | Florida | 33445 | — |
| Coral Clinical Research | Homestead | Florida | 33032 | — |
| K2 Medical Research - Villages | Lady Lake | Florida | 32159 | — |
| Finlay Medical Research | Miami | Florida | 33126 | — |
| Aqualane Clinical Research | Naples | Florida | 34105-8522 | — |
| Ocala Health - Family Care Specialists - Ocala I | Ocala | Florida | 34470 | — |
| Progressive Medical Research | Port Orange | Florida | 32127 | — |
| Alzheimer's Research and Treatment Center - Stuart | Stuart | Florida | 34997 | — |
| K2 Medical Research - Tampa | Tampa | Florida | 33607 | — |
| Charter Research - Lady Lake | The Villages | Florida | 32162 | — |
| Alzheimers Research and Treatment Center - Wellington | Wellington | Florida | 33414 | — |
| Conquest Research | Winter Park | Florida | 32789 | — |
| Charter Research - Winter Park | Winter Park | Florida | 32792 | — |
| Columbus Memory Center | Columbus | Georgia | 31909 | — |
| CenExel - iResearch Atlanta | Decatur | Georgia | 30030 | — |
| Office of Jeffrey S. Ross, MD | Northbrook | Illinois | 60640 | — |
| Boston Center for Memory | Newton | Massachusetts | 02459 | — |
| Hattiesburg Clinic - Memory Center | Hattiesburg | Mississippi | 39401-7246 | — |
| ActivMed Practices and Research | Portsmouth | New Hampshire | 03801 | — |
| The Cognitive and Research Center of New Jersey | Springfield | New Jersey | 07081 | — |
| CenExel - Advanced Memory Research Institute of NJ | Toms River | New Jersey | 08755 | — |
| Neurological Associates of Albany | Albany | New York | 12208 | — |
| AMC Research | Matthews | North Carolina | 28105 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| Summit Research Network | Portland | Oregon | 97210 | — |
| Abington Neurological Associates | Abington | Pennsylvania | 19001 | — |
| Keystone Clinical Research | Norristown | Pennsylvania | 19462 | — |
| Rhode Island Mood and Memory | East Providence | Rhode Island | 02914 | — |
| Neurology Clinic. P.C | Cordova | Tennessee | 38018 | — |
| The Alliance for Multispecialty Research LLC (AMR) | Knoxville | Tennessee | 37920-1511 | — |
| Senior Adult Specialty Research | Austin | Texas | 78757 | — |
| Gadolin Research, LLC | Beaumont | Texas | 77702 | — |
| Kerwin Medical Center | Dallas | Texas | 75231 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 24 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06335173, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 26, 2025 · Synced Apr 30, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06335173 live on ClinicalTrials.gov.