A Study of Lebrikizumab (LY3650150) in Participants With Chronic Rhinosinusitis and Nasal Polyps Treated With Intranasal Corticosteroids (CONTRAST-NP)
Public ClinicalTrials.gov record NCT06338995. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Evaluate the Efficacy and Safety of Lebrikizumab/LY3650150 in Participants With Chronic Rhinosinusitis With Nasal Polyps on Background Intranasal Corticosteroids
Study identification
- NCT ID
- NCT06338995
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Eli Lilly and Company
- Industry
- Enrollment
- 510 participants
Conditions and interventions
Interventions
- LY3650150 Drug
- Placebo Drug
- Standard therapy for INCS Drug
Drug
Eligibility (public fields only)
- Age range
- 12 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 28, 2024
- Primary completion
- Apr 30, 2027
- Completion
- Feb 29, 2028
- Last update posted
- May 18, 2026
2024 – 2028
United States locations
- U.S. sites
- 33
- U.S. states
- 17
- U.S. cities
- 29
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| AllerVie Clinical Research | Birmingham | Alabama | 35209 | Not yet recruiting |
| University of Alabama at Birmingham | Birmingham | Alabama | 35233 | Recruiting |
| Keck Medicine of USC | Arcadia | California | 91007 | Not yet recruiting |
| University of California, Irvine | Irvine | California | 92697 | Recruiting |
| DaVinci Research LLC | Roseville | California | 95661 | Recruiting |
| Breathe Clear Institute | Torrance | California | 90503 | Recruiting |
| Colorado ENT & Allergy | Colorado Springs | Colorado | 80923 | Recruiting |
| Orlando ENT & Allergy | Orlando | Florida | 32825 | Not yet recruiting |
| NuLine Clinical Trial Center | Pompano Beach | Florida | 33060 | Not yet recruiting |
| University of South Florida | Tampa | Florida | 33613 | Recruiting |
| Treasure Valley Medical Research | Boise | Idaho | 83706 | Recruiting |
| Entopy Research LLC | Chicago | Illinois | 60616 | Recruiting |
| Chicago ENT | Chicago | Illinois | 60657 | Recruiting |
| South Louisiana Ear, Nose, Throat & Facial Plastic Surgery - PPDS | Mandeville | Louisiana | 70471 | Recruiting |
| Chesapeake Clinical Research, Inc. | White Marsh | Maryland | 21162 | Recruiting |
| Brigham and Women's Hospital | Boston | Massachusetts | 02215 | Recruiting |
| University of Missouri | Columbia | Missouri | 65212 | Recruiting |
| Washington University School of Medicine | St Louis | Missouri | 63141 | Not yet recruiting |
| Circuit Clinical/Mercer Allergy and Pulmonary Associates | Hamilton | New Jersey | 08619 | Not yet recruiting |
| Madison ENT & Facial Plastic Surgery | New York | New York | 10016 | Recruiting |
| New York Allergy and Sinus Center | New York | New York | 10016 | Recruiting |
| Equity Medical | The Bronx | New York | 10455 | Recruiting |
| UCMC | Cincinnati | Ohio | 45267 | Not yet recruiting |
| Optimed Research, LTD | Columbus | Ohio | 43235 | Recruiting |
| Medical University of South Carolina- Department of Otolaryngology and Head and Neck Surgery | Charleston | South Carolina | 29425 | Not yet recruiting |
| Alina Clinical Trials | Dallas | Texas | 75209 | Recruiting |
| UT Southwestern Medical Center | Dallas | Texas | 75390-9035 | Not yet recruiting |
| University of Texas Physicians Department of Otorhinolaryngology Clinc | Houston | Texas | 77030 | Recruiting |
| Ear Nose and Throat Associates of Texas PA | McKinney | Texas | 75070-5735 | Recruiting |
| Alamo ENT Associates | San Antonio | Texas | 78258-3227 | Recruiting |
| Eastern Virginia Medical School | Norfolk | Virginia | 23507 | Recruiting |
| Richmond Ear Nose and Throat | Richmond | Virginia | 23235 | Not yet recruiting |
| The Medical College of Wisconsin | Milwaukee | Wisconsin | 53226-3548 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 159 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06338995, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 18, 2026 · Synced May 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06338995 live on ClinicalTrials.gov.