Clinical Trials Finder
Independent ClinicalTrials.gov directory
ClinicalTrials.gov record
Recruiting Phase 1 Interventional

Open-label Study of BBO-8520 in Adult Subjects With KRASG12C Non-small Cell Lung Cancer

ClinicalTrials.gov ID: NCT06343402

Public ClinicalTrials.gov record NCT06343402. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

View official ClinicalTrials.gov record → Back to search
ClinicalTrials.gov public records Last synced May 6, 2026, 7:33 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1a/1b Open-Label Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of BBO-8520 in Subjects With Advanced KRASG12C Mutant Non-Small Cell Lung Cancer - The ONKORAS-101 Study

Study identification

NCT ID
NCT06343402
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 1
Lead sponsor
TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)
Industry
Enrollment
350 participants

Conditions and interventions

Interventions

  • BBO-10203 Drug
  • BBO-8520 Drug
  • Pembrolizumab Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 21, 2024
Primary completion
Mar 31, 2031
Completion
Aug 31, 2031
Last update posted
May 4, 2026

2024 – 2031

United States locations

U.S. sites
22
U.S. states
15
U.S. cities
21
Facility City State ZIP Site status
O'Neal Comprehensive Cancer Center at UAB Birmingham Alabama 35233 Recruiting
University of California - San Diego Moores Cancer Center La Jolla California 92093 Recruiting
University of California San Francisco San Francisco California 94158 Recruiting
UCLA Health - Santa Monica Cancer Care Santa Monica California 90404 Recruiting
University of Colorado Cancer Center Aurora Colorado 80045 Recruiting
Yale Cancer Center New Haven Connecticut 06510 Recruiting
Norwalk Hospital Norwalk Connecticut 06850 Recruiting
OSF Saint Francis Medical Center Peoria Illinois 61603 Recruiting
University of Kansas Medical Center Kansas City Kansas 66205 Recruiting
Henry Ford Cancer - Detroit Detroit Michigan 48282 Recruiting
Roswell Park Cancer Institute Buffalo New York 14263 Recruiting
Perlmutter Cancer Center - NYU Langone Health New York New York 10016 Recruiting
Memorial Sloan Kettering Cancer Center New York New York 10065 Recruiting
Cleveland Clinic Cleveland Ohio 44195 Recruiting
USOR - Oncology Associates of Oregon, P.C Eugene Oregon 97401 Recruiting
SCRI Oncology Partners Nashville Tennessee 37203 Recruiting
Oncology Consultants Texas Medical Center Houston Texas 77030 Recruiting
USOR - Texas Oncology - (DFW) Waco Waco Texas 76710 Recruiting
Huntsman Cancer Institute Salt Lake City Utah 84112 Recruiting
NEXT Oncology Fairfax Virginia 22031 Recruiting
Fred Hutchinson Cancer Center Seattle Washington 98109 Recruiting
Northwest Medical Specialties Tacoma Washington 98405 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 13 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06343402, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 4, 2026 · Synced May 6, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06343402 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →