Study of Plozasiran in Adults With Severe Hypertriglyceridemia
Public ClinicalTrials.gov record NCT06347016. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Double-blind, Placebo-controlled, Phase 3 Study to Evaluate the Efficacy and Safety of Plozsiran in Adults With Severe Hypertriglyceridemia
Study identification
- NCT ID
- NCT06347016
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Arrowhead Pharmaceuticals
- Industry
- Enrollment
- 311 participants
Conditions and interventions
Conditions
Interventions
- Placebo Drug
- Plozasiran Injection Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 22, 2024
- Primary completion
- May 31, 2026
- Completion
- Aug 31, 2026
- Last update posted
- Oct 23, 2025
2024 – 2026
United States locations
- U.S. sites
- 50
- U.S. states
- 21
- U.S. cities
- 47
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site 1 | Birmingham | Alabama | 35205 | — |
| Research Site 2 | Mobile | Alabama | 36604 | — |
| Research Site 3 | Beverly Hills | California | 90211 | — |
| Research Site 4 | Canoga Park | California | 91303 | — |
| Research Site 5 | Huntington Beach | California | 92648 | — |
| Research Site 6 | Lincoln | California | 95648 | — |
| Research Site 7 | Long Beach | California | 90822 | — |
| Research Site 8 | Oxnard | California | 93030 | — |
| Research Site 9 | Clearwater | Florida | 33756 | — |
| Research Site 10 | North Miami | Florida | 33162 | — |
| Research Site 11 | Sarasota | Florida | 34239 | — |
| Research Site 12 | Lawrenceville | Georgia | 30044 | — |
| Research Site 13 | Sugar Hill | Georgia | 30518 | — |
| Research Site 14 | Elkhart | Indiana | 46514 | — |
| Research Site 15 | Indianapolis | Indiana | 46290 | — |
| Research Site 16 | South Bend | Indiana | 46617 | — |
| Research Site 17 | Overland Park | Kansas | 66211 | — |
| Research Site 18 | Topeka | Kansas | 66606 | — |
| Research Site 19 | Metairie | Louisiana | 70001 | — |
| Research Site 20 | Annapolis | Maryland | 21401 | — |
| Research Site 21 | Jackson | Mississippi | 39202 | — |
| Research Site 22 | Fremont | Nebraska | 68025 | — |
| Research Site 23 | Norfolk | Nebraska | 68701 | — |
| Research Site 24 | Morristown | New Jersey | 07960 | — |
| Research Site 26 | New York | New York | 10029 | — |
| Research Site 27 | Riverhead | New York | 11901 | — |
| Research Site 25 | The Bronx | New York | 10461 | — |
| Research Site 28 | Asheboro | North Carolina | 27203 | — |
| Research Site 29 | Wilmington | North Carolina | 28412 | — |
| Research Site 30 | Beavercreek | Ohio | 45431 | — |
| Research Site 31 | Columbus | Ohio | 43214 | — |
| Research Site 32 | Oklahoma City | Oklahoma | 73112 | — |
| Research Site 33 | Horsham | Pennsylvania | 19044 | — |
| Research Site 34 | Newport | Pennsylvania | 17074 | — |
| Research Site 35 | Philadelphia | Pennsylvania | 19104 | — |
| Research Site 36 | Philadelphia | Pennsylvania | 19104 | — |
| Research Site 37 | Fort Mill | South Carolina | 29707 | — |
| Research Site 38 | Greenville | South Carolina | 29607 | — |
| Research Site 39 | Chattanooga | Tennessee | 37411 | — |
| Research Site 40 | Fort Worth | Texas | 76132 | — |
| Research Site 41 | Houston | Texas | 77040 | — |
| Research Site 42 | Houston | Texas | 77090 | — |
| Research Site 43 | Houston | Texas | 77090 | — |
| Research Site 44 | Sugar Land | Texas | 77479 | — |
| Research Site 45 | Tomball | Texas | 77375 | — |
| Research Site 46 | Victoria | Texas | 77901 | — |
| Research Site 47 | Bountiful | Utah | 84010 | — |
| Research Site 48 | St. George | Utah | 84790 | — |
| Research Site 49 | Manassas | Virginia | 20110 | — |
| Research Site 50 | Roanoke | Virginia | 24014 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 99 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06347016, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 23, 2025 · Synced May 18, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06347016 live on ClinicalTrials.gov.