ClinicalTrials.gov record
Active, not recruiting Phase 2 Interventional

A Study of EDG-7500 in Adults With Hypertrophic Cardiomyopathy (CIRRUS-HCM)

ClinicalTrials.gov ID: NCT06347159

Public ClinicalTrials.gov record NCT06347159. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Apr 22, 2026, 8:26 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

An Open-label Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of EDG-7500 in Adults With Hypertrophic Cardiomyopathy

Study identification

NCT ID
NCT06347159
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 2
Lead sponsor
Edgewise Therapeutics, Inc.
Industry
Enrollment
100 participants

Conditions and interventions

Interventions

  • EDG-7500 Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Not listed

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 10, 2024
Primary completion
May 31, 2026
Completion
Nov 30, 2026
Last update posted
Feb 26, 2026

2024 – 2026

United States locations

U.S. sites
21
U.S. states
14
U.S. cities
19
Facility City State ZIP Site status
University of California, San Francisco San Francisco California 94143
Stanford University Hospital / Stanford Health Care Stanford California 94305
Emory Clinic Atlanta Georgia 30322
Massachusetts General Hospital Boston Massachusetts 02114
Brigham and Womens Hospital Boston Massachusetts 02115
Lahey Hospital and Medical Center Burlington Massachusetts 01805
Michigan Medicine - Michigan Clinical Research Unit Ann Arbor Michigan 48109
Saint Luke's Hospital of Kansas City Kansas City Missouri 64111
Morristown Medical Center (Atlantic Health System) Morristown New Jersey 07960
North Shore University Hospital Manhasset New York 11030
NYU Langone Health Medical Center - HCM Program Office (Study open to existing NYU patients only) New York New York 10016
Sanger Heart and Vascular Institute Charlotte North Carolina 28204
Duke Health Center Arringdon Morrisville North Carolina 27560
The Lindner Research Center at Christ Hospital Cincinnati Ohio 45219
University Hospitals Cleveland Medical Center Cleveland Ohio 33612
Cleveland Clinic Cleveland Ohio 44195
Oregon Health & Science University (OHSU) Portland Oregon 97239
Hospital of the University of Pennsylvania (University of Pennsylvania School of Medicine) Philadelphia Pennsylvania 19104
Medical University of South Carolina Charleston South Carolina 29425
University of Virginia Heart and Vascular Center Fontaine Charlottesville Virginia 22903
Virginia Mason Medical Center Seattle Washington 98101

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06347159, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 26, 2026 · Synced Apr 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06347159 live on ClinicalTrials.gov.

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