Safety and Efficacy of 0.75% Phentolamine Ophthalmic Solution in Subjects With Post-refractive Surgery Visual Disturbances
Public ClinicalTrials.gov record NCT06349759. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Randomized, Placebo-Controlled, Double-Masked Study of the Safety and Efficacy of POS (0.75% Phentolamine Ophthalmic Solution) in Subjects Who Have Previously Had Keratorefractive Surgery and Have Decreased Visual Acuity Under Mesopic Conditions
Study identification
- NCT ID
- NCT06349759
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Ocuphire Pharma, Inc.
- Industry
- Enrollment
- 200 participants
Conditions and interventions
Conditions
Interventions
- Placebo Drug
- phentolamine ophthalmic solution 0.75%, a non-selective alpha-1 and alpha-2 adrenergic antagonist Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 31, 2024
- Primary completion
- Apr 16, 2025
- Completion
- Feb 18, 2026
- Last update posted
- Mar 11, 2026
2024 – 2026
United States locations
- U.S. sites
- 25
- U.S. states
- 14
- U.S. cities
- 23
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| United States Phoenix | Pheonix | Arizona | 85003 | — |
| United States Scottsdale | Scottsdale | Arizona | 85260 | — |
| United States | Bakersfield | California | 93309 | — |
| United States, Glendale, CA | Glendale | California | 91204 | — |
| United States, LaJolla, CA | La Jolla | California | 92903 | — |
| United States, California | Newport Beach | California | 92663 | — |
| United States Rowland Heights | Rowland Heights | California | 91748 | — |
| United States Torrance | Torrance | California | 90505 | — |
| United States, Jacksonville, FL | Jacksonville | Florida | 32256 | — |
| United States Jacksonville | Jacksonville | Florida | 32257 | — |
| United States | Tampa | Florida | 33603 | — |
| United States Overland Park | Overland Park | Kansas | 66210 | — |
| United States Louisville | Louisville | Kentucky | 40206 | — |
| United States Fraser | Fraser | Michigan | 48026 | — |
| United States | New York | New York | 10022 | — |
| United States Smithtown | Smithtown | New York | 11787 | — |
| United States, North Carolina | Garner | North Carolina | 27529 | — |
| United States Fargo | Fargo | North Dakota | 58103 | — |
| United States | Fargo | North Dakota | 58103 | — |
| United States, Rhode Island | Warwick | Rhode Island | 02888 | — |
| United States, Mt Pleasant, SC | Mt. Pleasant | South Carolina | 29464 | — |
| United States Chattanooga | Chattanooga | Tennessee | 37411 | — |
| United States Smyrna | Smyrna | Tennessee | 37167 | — |
| United States Draper | Draper | Utah | 84020 | — |
| United States Lynchburg | Lynchburg | Virginia | 24502 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06349759, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 11, 2026 · Synced May 20, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06349759 live on ClinicalTrials.gov.