A Study to Evaluate Efficacy and Safety of MELT-300 for Procedural Sedation in Subjects Undergoing Cataract Extraction With Lens Replacement (CELR)
Public ClinicalTrials.gov record NCT06383273. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-Masked, Placebo-Controlled, Parallel-Group, Multi-Center Study to Evaluate Efficacy and Safety of MELT-300 for Procedural Sedation in Subjects Undergoing Cataract Extraction With Lens Replacement (CELR)
Study identification
- NCT ID
- NCT06383273
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Melt Pharmaceuticals
- Industry
- Enrollment
- 528 participants
Conditions and interventions
Conditions
Interventions
- MELT-300 sublingual tablet Drug
- Midalozam sublingual tablet Drug
- Placebo sublingual tablet Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 30, 2024
- Primary completion
- Nov 30, 2024
- Completion
- Dec 31, 2024
- Last update posted
- Aug 1, 2024
2024 – 2025
United States locations
- U.S. sites
- 12
- U.S. states
- 11
- U.S. cities
- 12
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Ridge Eye Care, Inc. | Chico | California | 95928 | Recruiting |
| Icon Eye Care | Grand Junction | Colorado | 81501 | Recruiting |
| Levenson Eye Associates | Jacksonville | Florida | 32204 | Recruiting |
| Maryland Vision Institute | Hagerstown | Maryland | 21740 | Recruiting |
| Vance Thompson Vision- Alexandria | Alexandria | Minnesota | 56308 | Recruiting |
| Tekwani Vision Center | Bay Saint Louis | Mississippi | 63128 | Recruiting |
| Bergstrom Eye Research | Fargo | North Dakota | 58103 | Recruiting |
| Vance Thompson Vision, ND | West Fargo | North Dakota | 58078 | Recruiting |
| Northeastern Eye Institute | Scranton | Pennsylvania | 18503 | Recruiting |
| Conway Ophthalmology | Conway | South Carolina | 29526 | Recruiting |
| Vance Thompson Vision | Sioux Falls | South Dakota | 57108 | Recruiting |
| Utah Eye Centers- Pleasant Grove | Pleasant Grove | Utah | 84062 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06383273, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 1, 2024 · Synced May 21, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06383273 live on ClinicalTrials.gov.