A Randomized, Controlled, Safety and Tolerability Study of VRDN-001 in Participants With Thyroid Eye Disease (TED)
Public ClinicalTrials.gov record NCT06384547. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Controlled, Safety and Tolerability Study of VRDN-001, a Humanized Monoclonal Antibody Directed Against the IGF-1 Receptor, in Participants With Thyroid Eye Disease (TED)
Study identification
- NCT ID
- NCT06384547
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Viridian Therapeutics, Inc.
- Industry
- Enrollment
- 231 participants
Conditions and interventions
Conditions
Interventions
- VRDN-001 10 mg/kg Drug
- VRDN-001 3 mg/kg Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 22, 2024
- Primary completion
- Apr 30, 2025
- Completion
- Jan 18, 2026
- Last update posted
- Apr 29, 2026
2024 – 2026
United States locations
- U.S. sites
- 26
- U.S. states
- 14
- U.S. cities
- 23
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| United Medical Research Institute | Inglewood | California | 90301 | — |
| Advancing Research International, LLC | Los Angeles | California | 90023 | — |
| Stanford Byers Eye Institute | Palo Alto | California | 94303 | — |
| Cockerham Eye Consultants, PC | San Diego | California | 92108 | — |
| FOMAT Medical Research | Santa Maria | California | 93454 | — |
| University of Colorado - Dept of Ophthalmology | Aurora | Colorado | 80045 | — |
| Sina Medical Center LLC | Homestead | Florida | 33034 | — |
| Med-Care Research Inc. | Miami | Florida | 33125 | — |
| Edward Jenner Research Group Center LLC | Plantation | Florida | 33317 | — |
| Sarasota Retina Institute | Sarasota | Florida | 34231 | — |
| Vision Medical Research Inc. | Orland Park | Illinois | 60462 | — |
| University Health Diabetes, Endocrinology & Nephrology Center | Kansas City | Kansas | 64108 | — |
| KU Medical Center, University of Kansas | Kansas City | Kansas | 66103 | — |
| Massachusetts Eye and Ear | Boston | Massachusetts | 02114 | — |
| Ophthalmic Consultants of Boston | Weymouth | Massachusetts | 02189 | — |
| Fraser Eye Care Center | Fraser | Michigan | 48026 | — |
| Kahana Oculoplastic & Orbital Surgery | Livonia | Michigan | 48152 | — |
| University of Minnesota, Department of Ophthalmology and Visual Neurosciences | Minneapolis | Minnesota | 55455 | — |
| Advancing Research International, LLC | Las Vegas | Nevada | 89144 | — |
| Rutgers- New Jersey Medical School- Newark | Newark | New Jersey | 07103 | — |
| New York Eye Ear Infirmary of Mount Sinai | New York | New York | 10003 | — |
| Baylor College of Medicine (BCM) - Ophthalmology | Houston | Texas | 77030 | — |
| Neuro-Eye Clinical Trials | Houston | Texas | 77074 | — |
| Neuro-Ophthalmology of Texas, PLLC | Houston | Texas | 77074 | — |
| University of Vermont Medical Center | Burlington | Vermont | 05401 | — |
| West Virginia University Eye Institute | Morgantown | West Virginia | 26506 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 24 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06384547, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 29, 2026 · Synced May 18, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06384547 live on ClinicalTrials.gov.