JAB-30355 in Patients With Advanced Solid Tumors Harboring TP53 Y220C Mutation
Public ClinicalTrials.gov record NCT06386146. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1/2a, Multi-Center, Open-Label Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Evidence of Antitumor Activity of JAB-30355 in Adult Patients With Advanced Solid Tumors Harboring TP53 Y220C Mutation
Study identification
- NCT ID
- NCT06386146
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Lead sponsor
- Jacobio Pharmaceuticals Co., Ltd.
- Industry
- Enrollment
- 144 participants
Conditions and interventions
Conditions
Interventions
- JAB-30355 Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 23, 2024
- Primary completion
- Dec 31, 2026
- Completion
- Jun 30, 2027
- Last update posted
- Jan 21, 2026
2024 – 2027
United States locations
- U.S. sites
- 7
- U.S. states
- 6
- U.S. cities
- 7
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Denver | Colorado | 80218 | Recruiting |
| Research site | Lake Mary | Florida | 32771 | Recruiting |
| Research site | St Louis | Missouri | 63110 | Recruiting |
| Research site | Canton | Ohio | 44718 | Terminated |
| Research site | Cleveland | Ohio | 44195 | Recruiting |
| Research Site | Nashville | Tennessee | 37203 | Recruiting |
| Research site | Houston | Texas | 77030 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 6 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06386146, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 21, 2026 · Synced Apr 22, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06386146 live on ClinicalTrials.gov.