Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)
Public ClinicalTrials.gov record NCT06395103. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
LIGHTBEAM-U01 Substudy 01A: A Phase 1/2 Substudy to Evaluate the Safety and Efficacy of Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors
Study identification
- NCT ID
- NCT06395103
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Lead sponsor
- Merck Sharp & Dohme LLC
- Industry
- Enrollment
- 90 participants
Conditions and interventions
Conditions
Interventions
- Zilovertamab vedotin Biological
Biological
Eligibility (public fields only)
- Age range
- 6 Months to 25 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 15, 2024
- Primary completion
- Mar 30, 2029
- Completion
- Mar 30, 2029
- Last update posted
- Apr 12, 2026
2024 – 2029
United States locations
- U.S. sites
- 17
- U.S. states
- 16
- U.S. cities
- 17
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Children's Hospital Los Angeles ( Site 1006) | Los Angeles | California | 90027 | Recruiting |
| Children's Hospital Colorado-Center for Cancer and Blood Disorders ( Site 1016) | Aurora | Colorado | 80045 | Recruiting |
| Yale New Haven Hospital ( Site 1012) | New Haven | Connecticut | 06510 | Recruiting |
| Johns Hopkins All Children's Hospital ( Site 1025) | St. Petersburg | Florida | 33701 | Recruiting |
| University of Iowa-Holden Comprehensive Cancer Center ( Site 1017) | Iowa City | Iowa | 52242 | Recruiting |
| Dana-Farber Cancer Institute ( Site 1013) | Boston | Massachusetts | 02215 | Recruiting |
| Corewell Health ( Site 1001) | Grand Rapids | Michigan | 49503 | Recruiting |
| Children's Mercy Hospital ( Site 1024) | Kansas City | Missouri | 64108 | Recruiting |
| Rutgers Cancer Institute of New Jersey ( Site 1008) | New Brunswick | New Jersey | 08903 | Recruiting |
| Memorial Sloan Kettering Cancer Center ( Site 1010) | New York | New York | 10065 | Recruiting |
| New York Medical College ( Site 1023) | Valhalla | New York | 10595 | Recruiting |
| Sanford Fargo Medical Center-Roger Maris Cancer Center ( Site 1003) | Fargo | North Dakota | 58102 | Recruiting |
| Oregon Health and Science University ( Site 1004) | Portland | Oregon | 97239 | Recruiting |
| Children's Hospital of Philadelphia (CHOP) ( Site 1021) | Philadelphia | Pennsylvania | 19104 | Recruiting |
| Sanford Children's Hospital-Sanford Children's Specialty Clinic ( Site 1015) | Sioux Falls | South Dakota | 57105 | Recruiting |
| University of Texas MD Anderson Cancer Center ( Site 1007) | Houston | Texas | 77030 | Recruiting |
| Intermountain - Primary Children's Hospital ( Site 1014) | Salt Lake City | Utah | 84113 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 50 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06395103, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 12, 2026 · Synced May 8, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06395103 live on ClinicalTrials.gov.