An Observational Study of Etrasimod in Adult Patients With Moderate to Severe Ulcerative Colitis

ClinicalTrials.gov ID: NCT06398626

Public ClinicalTrials.gov record NCT06398626. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Sep 2, 2026, 6:45 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multi-Center, Prospective, Non-Interventional Study of Real-World Effectiveness of Etrasimod in Patients With Ulcerative Colitis (ENDEAVOUR-UC)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this observational study is to learn about the effects of etrasimod as a treatment for adult patients with moderate to severe ulcerative colitis. Patients will be treated according to standard of care and will only be included in the study if etrasimod is the best treatment of choice according to the physician and they have not previously taken etrasimod. All patients will be prescribed etrasimod according to standard of care. Tests and doctor visits will be conducted according to standard of care with the exception of health questionnaires about ulcerative colitis symptoms. These questionnaires will be completed by patients at various timepoints during the study using their mobile phone, tablet, or computer. The study is 52 weeks with 28 days of safety follow up. The effects of etrasimod will be analyzed for each patient comparing their disease activity prior to the start of etrasimod.

Study identification

NCT ID: NCT06398626
Recruitment status: Recruiting
Study type: Observational
Phase: Not listed
Lead sponsor: Pfizer; Industry
Enrollment: 300 participants

Conditions and interventions

Conditions

Colitis, Ulcerative

Interventions

Etrasimod Drug

Drug

Eligibility (public fields only)

Age range: 18 Years to 64 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Sep 16, 2024
Primary completion: Sep 30, 2027
Completion: Jul 6, 2028
Last update posted: Jul 8, 2026

2024 – 2028

United States locations

U.S. sites: 26
U.S. states: 14
U.S. cities: 23

Facility	City	State	ZIP	Site status
Reddy GI Associates	Mesa	Arizona	85206	Recruiting
Scripps Clinic Torrey Pines	La Jolla	California	92037	Recruiting
United Medical Doctors	Los Alamitos	California	90720	Not yet recruiting
Rocky Mountain Gastroenterology	Littleton	Colorado	80120	Recruiting
Digestive and Liver Center of Florida Kissimmee	Kissimmee	Florida	34741	Recruiting
Gastro Florida	Lutz	Florida	33558	Terminated
Orlando Health/Digestive Health Institute	Orlando	Florida	32806	Not yet recruiting
Feinberg School of Medicine Northwestern University	Chicago	Illinois	60611	Recruiting
Rush University Medical Center	Chicago	Illinois	60612	Recruiting
Suburban Gastroenterology Ltd	Naperville	Illinois	60540	Recruiting
MGG Group Co., Inc., Chevy Chase Clinical Research	Chevy Chase	Maryland	20815	Recruiting
Woodholme Gastroenterology Associates PA	Glen Burnie	Maryland	21061	Recruiting
Virtua Health	Marlton	New Jersey	08053	Recruiting
NYU Langone Health	New York	New York	10016	Recruiting
Lenox Hill Hospital, Northwell Health	New York	New York	10075	Recruiting
University of North Carolina at Chapel Hill, Division of Gastroenterology and Hepatology	Chapel Hill	North Carolina	27599	Recruiting
OnSite Clinical Solutions, LLC	Charlotte	North Carolina	28211	Recruiting
University of Cincinnati College of Medicine	Cincinnati	Ohio	45267	Recruiting
Gastro Intestinal Research Institute of Northern Ohio, LLC	Westlake	Ohio	44145	Recruiting
Medical University of South Carolina (MUSC)	Charleston	South Carolina	29425	Recruiting
Houston Endoscopy & Research Center	Houston	Texas	77079	Recruiting
BI Research Center	Houston	Texas	77084	Recruiting
Brooke Army Medical center	San Antonio	Texas	78234	Not yet recruiting
GI Alliance Research	Southlake	Texas	76092	Recruiting
Washington Gastroenterology	Tacoma	Washington	98405	Recruiting
WVU Medicine J.W Ruby Memorial Hospital	Morgantown	West Virginia	26505	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT06398626, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Jul 8, 2026 · Synced Sep 2, 2026

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The complete protocol, eligibility criteria, and contact information for NCT06398626 live on ClinicalTrials.gov.

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