A Study to Investigate APL-5125 in Adults With Advanced Solid Tumors

ClinicalTrials.gov ID: NCT06399757

Public ClinicalTrials.gov record NCT06399757. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 18, 2026, 6:07 AM EDT

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Official title

A Phase 1/2 Study to Assess the Safety and Antitumor Activity of APL-5125 in Adults With Selected Advanced Solid Tumors

Study identification

NCT ID: NCT06399757
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 1, Phase 2
Lead sponsor: Apollo Therapeutics Ltd; Industry
Enrollment: 100 participants

Conditions and interventions

Conditions

Interventions

APL-5125 Drug

Drug

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Jun 17, 2024
Primary completion: Mar 31, 2027
Completion: Apr 30, 2027
Last update posted: Jan 6, 2026

2024 – 2027

United States locations

U.S. sites: 9
U.S. states: 6
U.S. cities: 9

Facility	City	State	ZIP	Site status
City of Hope	Duarte	California	91010	Active, not recruiting
City of Hope Orange County Lennar Foundation Cancer Center	Irvine	California	92618	Active, not recruiting
Florida Cancer Specialists & Research Institute	Sarasota	Florida	34232	Recruiting
University of Michigan	Ann Arbor	Michigan	48109	Recruiting
Duke Cancer Institute	Durham	North Carolina	27710	Recruiting
Carolina BioOncology Institute	Huntersville	North Carolina	28078	Recruiting
Medical University of South Carolina	Charleston	South Carolina	29425	Recruiting
Mary Crowley Cancer Research	Dallas	Texas	75251	Recruiting
NEXT Oncology- San Antonio	San Antonio	Texas	78229	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT06399757, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Jan 6, 2026 · Synced May 18, 2026

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The complete protocol, eligibility criteria, and contact information for NCT06399757 live on ClinicalTrials.gov.

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