RECOVER-ENERGIZE Platform Protocol
Public ClinicalTrials.gov record NCT06404047. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
RECOVER-ENERGIZE: A Platform Protocol for Evaluation of Interventions for Exercise Intolerance in Post-Acute Sequelae of SARS-CoV-2 Infection (PASC)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a platform protocol designed to be flexible so that it is suitable for a range of interventions and settings within diverse health care systems and community settings with incorporation into clinical COVID-19 management programs and treatment plans if results achieve key study outcomes. This protocol is a prospective, multi-center, multi-arm, randomized, controlled platform trial evaluating interventions to address and improve exercise intolerance and post-exertional malaise (PEM) as manifestations of Post-Acute Sequelae of SARS-CoV-2 Infection (PASC). The focus of this protocol is to assess interventions that can improve exercise capacity, daily activities tolerance, and quality of life in patients with PASC.
Study identification
- NCT ID
- NCT06404047
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 660 participants
Conditions and interventions
Conditions
Interventions
- Personalized Cardiopulmonary Rehabilitation Behavioral
- Structured Pacing Behavioral
- Education Other
- Usual Care Other
Behavioral · Other
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 17, 2024 (Actual)
- Primary completion
- Oct 30, 2025 (Actual)
- Completion
- Oct 30, 2025 (Actual)
- Last update posted
- Nov 14, 2025
2024 – 2025
United States locations
- U.S. sites
- 42
- U.S. states
- 27
- U.S. cities
- 36
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35205 | — |
| Banner University Medical Center Phoenix | Phoenix | Arizona | 85006 | — |
| Banner University Medical Center Tucson | Tucson | Arizona | 85719 | — |
| Stanford University | Stanford | California | 94035 | — |
| Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center | Torrance | California | 90509 | — |
| University of Colorado | Aurora | Colorado | 80045 | — |
| Yale - New Haven Hospital | New Haven | Connecticut | 06520-8017 | — |
| University of Florida College of Medicine Jacksonville | Jacksonville | Florida | 32209 | — |
| Innovation Clinical Trials Inc. | Miami | Florida | 33144 | — |
| Valencia Medical and Research Center | Miami | Florida | 33165 | — |
| Grady Memorial Hospital (Emory) | Atlanta | Georgia | 30303 | — |
| Emory Hope Clinic | Decatur | Georgia | 30030 | — |
| University of Illinois at Chicago | Chicago | Illinois | 60608 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| North Shore University HealthSystem/Evanston Hospital | Evanston | Illinois | 60201 | — |
| Saint Francis Medical Center | Peoria | Illinois | 61637 | — |
| Cedar Valley Clinical Research | Waterloo | Iowa | 50701 | — |
| Kansas University Medical Center | Kansas City | Kansas | 66160 | — |
| University of Kentucky | Lexington | Kentucky | 40536 | — |
| Maine Health Institute of Research | Scarborough | Maine | 04074 | — |
| Tufts Medical Center | Boston | Massachusetts | 02111 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| Beth Israel Deaconess Med. Ctr. | Boston | Massachusetts | 02215 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Dartmouth Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | — |
| University of New Mexico Health Sciences Center | Albuquerque | New Mexico | 87102 | — |
| NYU Langone Health/Brooklyn Hospital | Brooklyn | New York | 11220 | — |
| University of North Carolina Hospital | Chapel Hill | North Carolina | 27514 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| Oregon Health and Science University | Portland | Oregon | 97239-3098 | — |
| University of Pittsburgh | Pittsburgh | Pennsylvania | 15213 | — |
| Avera McKennan Hospital & University Health Center | Sioux Falls | South Dakota | 57108 | — |
| Southwest Family Medicine Associates | Dallas | Texas | 75235 | — |
| Houston Methodist Hospital | Houston | Texas | 77030 | — |
| University of Texas Health Science Center at Houston | Houston | Texas | 77030 | — |
| University of Utah | Salt Lake City | Utah | 84132 | — |
| Vermont Lung Center, University of Vermont | Colchester | Vermont | 05446 | — |
| University Physicians and Surgeons, Inc dba Marshall Health | Huntington | West Virginia | 25701 | — |
| West Virginia Clinical and Translational Science Institute | Morgantown | West Virginia | 26506 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06404047, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 14, 2025 · Synced Oct 20, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06404047 live on ClinicalTrials.gov.